2022
COVID-19 Vaccine Hesitancy Among Medicare Beneficiaries with and Without Cancer History: A US Population-based Study
Poghosyan H, Ni Z, Vlahov D, Nelson L, Nam S. COVID-19 Vaccine Hesitancy Among Medicare Beneficiaries with and Without Cancer History: A US Population-based Study. Journal Of Community Health 2022, 48: 315-324. PMID: 36427111, PMCID: PMC9702715, DOI: 10.1007/s10900-022-01174-5.Peer-Reviewed Original ResearchMeSH KeywordsAgedCOVID-19COVID-19 VaccinesCross-Sectional StudiesHumansMedicareNeoplasmsUnited StatesVaccinationConceptsCOVID-19 vaccineCOVID-19 vaccine hesitancyCancer historyVaccine hesitancyMedicare beneficiariesVaccine uptakeMultivariable logistic regression modelCOVID-19 vaccine uptakeVaccine hesitancy ratesOngoing health conditionsCOVID-19 vaccinationLogistic regression modelsComplex survey designLack of recommendationsHesitancy ratesVaccine benefitsCommon reasonHesitant individualsSide effectsUS populationVaccineHealth conditionsCross-sectional dataHesitancyRegression models
2013
Opioid Receptor Polymorphism A118G Associated with Clinical Severity in a Drug Overdose Population
Manini A, Jacobs M, Vlahov D, Hurd Y. Opioid Receptor Polymorphism A118G Associated with Clinical Severity in a Drug Overdose Population. Journal Of Medical Toxicology 2013, 9: 148-154. PMID: 23318993, PMCID: PMC3648633, DOI: 10.1007/s13181-012-0286-3.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlternative SplicingAmino Acid SubstitutionBenzodiazepinesCohort StudiesDrug OverdoseFemaleFollow-Up StudiesGenetic Association StudiesGenetic Predisposition to DiseaseHeart ArrestHumansMaleNarcoticsPilot ProjectsPolymorphism, Single NucleotideProspective StudiesReceptors, Opioid, muRespiratory InsufficiencySeverity of Illness IndexSympathomimeticsUnited StatesConceptsAcute drug overdoseG variant alleleClinical severityVariant allelesEmergency departmentDrug overdoseSingle nucleotide polymorphismsConsecutive adult ED patientsHuman mu-opioid receptor geneReceptor single nucleotide polymorphismsWorse clinical severityAdult ED patientsObservational cohort studyUrban teaching hospitalMu-opioid receptor geneAbove single nucleotide polymorphismsCohort studyED patientsRespiratory arrestCardiac arrestClinical variablesAcute drugSevere outcomesTeaching hospitalBlood samples
2007
Identifying injection drug users at risk of nonfatal overdose.
Coffin P, Tracy M, Bucciarelli A, Ompad D, Vlahov D, Galea S. Identifying injection drug users at risk of nonfatal overdose. Academic Emergency Medicine 2007, 14: 616-23. PMID: 17554010, DOI: 10.1197/j.aem.2007.04.005.Peer-Reviewed Original ResearchConceptsDrug usersHabitual drug usersNonfatal overdoseAggressive prevention effortsAgonist maintenance treatmentSerious withdrawal symptomsInjection drug usersFurther longitudinal studiesIndividual-level risk factorsTake-home naloxoneOverdose prevention interventionsFuture overdosesMaintenance treatmentWithdrawal symptomsRisk factorsDrug overdoseRecent overdoseEmergency physiciansOverdose riskPrevention interventionsHigh riskOverdoseMedical careYounger ageU.S. adults
2005
Haplotype analysis of the SDF-1 (CXCL12) gene in a longitudinal HIV-1/AIDS cohort study
Modi W, Scott K, Goedert J, Vlahov D, Buchbinder S, Detels R, Donfield S, O'Brien S, Winkler C. Haplotype analysis of the SDF-1 (CXCL12) gene in a longitudinal HIV-1/AIDS cohort study. Genes & Immunity 2005, 6: 691-698. PMID: 16177829, DOI: 10.1038/sj.gene.6364258.Peer-Reviewed Original ResearchMeSH KeywordsAcquired Immunodeficiency SyndromeAdolescentAdultAllelesBlack or African AmericanChemokine CXCL12Chemokines, CXCChildCohort StudiesDisease ProgressionFemaleGene FrequencyHaplotypesHIV InfectionsHIV-1HumansLongitudinal StudiesMaleOdds RatioPolymorphism, Single NucleotideRisk FactorsSurvival AnalysisUnited StatesWhite PeopleConceptsSDF-1 geneCohort studySingle nucleotide polymorphismsAfrican AmericansOnly natural ligandSingle disease outcomesX4 HIV-1HIV-1 infectionAIDS Cohort StudyRisk of infectionMACS cohortDisease outcomeHIV-1Epidemiological studiesSDF-1Significant associationChemokine genesInfectionRs1801157Natural ligandProgressionHaplotype analysisCommon haplotypeCXCR4CohortDrug use, misuse, and the urban environment
GALEA S, RUDENSTINE S, VLAHOV D. Drug use, misuse, and the urban environment. Drug And Alcohol Review 2005, 24: 127-136. PMID: 16076582, DOI: 10.1080/09595230500102509.Peer-Reviewed Original ResearchThe urban health “advantage”
Vlahov D, Galea S, Freudenberg N. The urban health “advantage”. Journal Of Urban Health 2005, 82: 1-4. PMID: 15738341, PMCID: PMC3456628, DOI: 10.1093/jurban/jti001.Peer-Reviewed Original Research
2004
Comparison of HIV infection risk behaviors among injection drug users from East and West Coast US cities
Garfein R, Monterroso E, Tong T, Vlahov D, Des Jarlais D, Selwyn P, Kerndt P, Word C, Fernando M, Ouellet L, Holmberg S. Comparison of HIV infection risk behaviors among injection drug users from East and West Coast US cities. Journal Of Urban Health 2004, 81: 260-267. PMID: 15136659, PMCID: PMC3456450, DOI: 10.1093/jurban/jth112.Peer-Reviewed Original ResearchConceptsInjection drug usersRisk behaviorsHIV seroprevalenceHigh human immunodeficiency virus (HIV) seroprevalenceDrug usersHIV infection risk behaviorsHuman immunodeficiency virus (HIV) seroprevalenceInfection risk behaviorsPotential risk factorsHIV risk behaviorsHIV incidenceHIV statusRisk factorsVirus seroprevalenceSexual partnersPrevention effortsSeroprevalenceBaseline dataHIVFace interviewsInjectionNew York CityFurther effortsNew HavenParticipants
2003
Understanding the dynamics of sexual transmission of HIV among drug-using populations: An integration of biological, behavioral, and environmental perspectives
Normand J, Lambert E, Vlahov D. Understanding the dynamics of sexual transmission of HIV among drug-using populations: An integration of biological, behavioral, and environmental perspectives. Journal Of Urban Health 2003, 80: iii1-iii6. PMID: 14713666, PMCID: PMC3456263, DOI: 10.1093/jurban/jtg077.Peer-Reviewed Original ResearchThe Role of Medicaid HMO Enrollment in the Longitudinal Utilization of Medical Care Services in a Cohort of Injecting Drug users in Baltimore, Maryland
Juday T, Wu A, Celentano D, Rick K, Wang M, Vlahov D. The Role of Medicaid HMO Enrollment in the Longitudinal Utilization of Medical Care Services in a Cohort of Injecting Drug users in Baltimore, Maryland. Substance Abuse 2003, 24: 27-41. PMID: 12652093, DOI: 10.1080/08897070309511531.Peer-Reviewed Original ResearchConceptsAmbulatory care visitsCare visitsInpatient admissionsHMO enrollmentDrug usersMedicaid HMO enrolleesMore inpatient admissionsInjecting Drug UsersMedical care utilizationNatural history studiesIntravenous Experience (ALIVE) studyMedical care servicesCommunity-based sampleLongitudinal utilizationER visitsHIV infectionCare utilizationMedicaid beneficiariesHMO enrolleesCare servicesIDUsInappropriate utilizationUtilization differencesMedicaidMedicaid HMOs
2002
Does Bleach Disinfection of Syringes Protect Against Hepatitis C Infection Among Young Adult Injection Drug Users?
Kapadia F, Vlahov D, Jarlais D, Strathdee S, Ouellet L, Kerndt P, E E, Williams I, Garfein R. Does Bleach Disinfection of Syringes Protect Against Hepatitis C Infection Among Young Adult Injection Drug Users? Epidemiology 2002, 13: 738-741. PMID: 12410020, DOI: 10.1097/00001648-200211000-00023.Peer-Reviewed Original ResearchConceptsInjection drug usersAnti-HCV seroconversionHepatitis C virusDrug usersOdds ratioBleach useYoung adult injection drug usersSeronegative injection drug usersMajor public health problemAdult injection drug usersBleach disinfectionHepatitis C infectionProspective cohort studyCase-control studyConditional logistic regressionPublic health problemCessation of injectionsC infectionHCV infectionCohort studyC virusProtective effectHealth problemsSeroconversionLogistic regressionRegional variation in CCR5-Δ32 gene distribution among women from the US HIV Epidemiology Research Study (HERS)
Downer M, Hodge T, Smith D, Qari S, Schuman P, Mayer K, Klein R, Vlahov D, Gardner L, McNicholl J. Regional variation in CCR5-Δ32 gene distribution among women from the US HIV Epidemiology Research Study (HERS). Genes & Immunity 2002, 3: 295-298. PMID: 12140749, DOI: 10.1038/sj.gene.6363884.Peer-Reviewed Original ResearchConceptsHIV Epidemiology Research StudyRace/ethnicityHIV-1HIV Epidemiologic Research StudyAfrican AmericansCCR5-Δ32 genotypeHIV-1 transmissionEpidemiologic research studiesHost genetic factorsHispanic/LatinaBlack/African AmericanUninfected womenAA womenUS womenCCR5-Δ32US populationWhite womenFrequency of heterozygotesWomenGenetic factorsDistributions of heterozygotesRegional variationResearch studiesSocial determinants and the health of drug users: socioeconomic status, homelessness, and incarceration.
Galea S, Vlahov D. Social determinants and the health of drug users: socioeconomic status, homelessness, and incarceration. Public Health Reports 2002, 117 Suppl 1: s135-45. PMID: 12435837, PMCID: PMC1913691.Peer-Reviewed Original ResearchConceptsDrug usersHealth consequencesSocioeconomic statusAdverse health consequencesPublic health interventionsIllicit drug useLow socioeconomic statusDrug use behaviorsDrug useHealth interventionsIndividual drug use behaviorRisk behaviorsSocial determinantsSocial factorsHealthStatusHigh levelsMedicationsFactors
2001
Prevalence, incidence, and correlates of chlamydia and gonorrhea among young adult injection drug users
Latka M, Ahern J, Garfein R, Ouellet L, Kerndt P, Morse P, Farshy C, Jarlais D, Vlahov D. Prevalence, incidence, and correlates of chlamydia and gonorrhea among young adult injection drug users. Journal Of Substance Abuse 2001, 13: 73-88. PMID: 11547626, DOI: 10.1016/s0899-3289(01)00071-2.Peer-Reviewed Original ResearchConceptsCorrelates of chlamydiaInjection drug usersYoung adult injection drug usersDrug usersSexual debutAdult injection drug usersAfrican American raceRecent sexual behaviorCumulative incidenceIDU populationPrevalent infectionChlamydia prevalenceGonorrhea prevalenceIncidence rateAmerican raceStandardized questionnaireGonorrheaYounger ageChlamydiaLogistic regressionPrevalenceDisease prevalenceIncidenceWomenSexual behavior
2000
Prevention of HIV Infection in Street-Recruited Injection Drug Users
Monterroso E, Hamburger M, Vlahov D, Jarlais D, Ouellet L, Altice F, Byers R, Kerndt P, Watters J, Bowser B, Fernando D, Holmberg S. Prevention of HIV Infection in Street-Recruited Injection Drug Users. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2000, 25: 63-70. DOI: 10.1097/00126334-200009010-00009.Peer-Reviewed Original ResearchConceptsInjection drug usersDrug usersHIV infectionInitial serum specimensLarge multicity studyHIV prevention strategiesHIV infection riskHIV prevention programsSyringe exchange programsDrug treatment programsUse of needlesNew AIDSHIV acquisitionHIV serostatusHIV casesPrevention strategiesSerum specimensSex partnersInfection ratePrevention programsTreatment programInfection riskStandard questionnaireHIVMultivariate modelPrevention of HIV Infection in Street-Recruited Injection Drug Users
Monterroso E, Hamburger M, Vlahov D, Jarlais D, Ouellet L, Altice F, Byers R, Kerndt P, Watters J, Bowser B, Fernando M, Holmberg S. Prevention of HIV Infection in Street-Recruited Injection Drug Users. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2000, 25: 63-70. PMID: 11064506, DOI: 10.1097/00042560-200009010-00009.Peer-Reviewed Original ResearchConceptsInjection drug usersDrug usersHIV infectionInitial serum specimensLarge multicity studyHIV prevention strategiesHIV infection riskHIV prevention programsSyringe exchange programsDrug treatment programsUse of needlesNew AIDSHIV acquisitionHIV serostatusHIV casesPrevention strategiesSerum specimensSex partnersInfection ratePrevention programsTreatment programInfection riskStandard questionnaireHIVMultivariate model
1999
Self-Reported Bacterial Infections Among Women with or at Risk for Human Immunodeficiency Virus Infection
Flanigan T, Hogan J, Smith D, Schoenbaum E, Vlahov D, Schuman P, Mayer K. Self-Reported Bacterial Infections Among Women with or at Risk for Human Immunodeficiency Virus Infection. Clinical Infectious Diseases 1999, 29: 608-612. PMID: 10530455, DOI: 10.1086/598641.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virus (HIV) infectionCD4 cell countImmunodeficiency virus infectionBacterial infectionsRecent pneumoniaVirus infectionCell countHIV-negative womenHIV-seropositive womenUrinary tract infectionInjection drug useLogistic regression analysisSelf-reported pneumoniaCross-sectional analysisSeronegative womenTract infectionsHIV infectionDrug useLifetime historyInfectionPneumoniaMajor causeWomenRegression analysisCell categoriesPre-AIDS Mortality and Morbidity among Injection Drug Users in Amsterdam and Baltimore: An Ecological Comparison
van Ameijden E, Krol A, Vlahov D, Flynn C, van Haastrecht H, Coutinho R. Pre-AIDS Mortality and Morbidity among Injection Drug Users in Amsterdam and Baltimore: An Ecological Comparison. Substance Use & Misuse 1999, 34: 845-865. PMID: 10227114, DOI: 10.3109/10826089909037245.Peer-Reviewed Original ResearchMeSH KeywordsAdultAmphetaminesBaltimoreCause of DeathCocaineCohort StudiesComorbidityCost ControlCross-Cultural ComparisonDrug OverdoseEthanolFemaleHealth Services AccessibilityHeroinHIV SeropositivityHospitalizationHumansMaleMethadoneNetherlandsRisk FactorsSubstance Abuse, IntravenousSuicideSurvival RateUnited StatesConceptsDrug usersHigh-dose methadone maintenanceIncidence of hospitalizationSuicide mortalityEmergency room visitsInjection drug usersDifferent health care systemsHealth care systemHIV seropositivityRoom visitsHospital visitsMethadone maintenancePrimary careRecent injectingRisk factorsAIDS mortalityLower mortalityPolydrug useMortalityCare systemSocietal costsMorbidityVisitsHospitalizationBaltimoreDirect Comparison of Time to AIDS and Infectious Disease Death Between HIV Seroconverter Injection Drug Users in Italy and the United States: Results From the ALIVE and ISS Studies
Pezzotti P, Galai N, Vlahov D, Rezza G, Lyles C, Astemborski J. Direct Comparison of Time to AIDS and Infectious Disease Death Between HIV Seroconverter Injection Drug Users in Italy and the United States: Results From the ALIVE and ISS Studies. JAIDS Journal Of Acquired Immune Deficiency Syndromes 1999, 20: 275-282. PMID: 10077177, DOI: 10.1097/00042560-199903010-00010.Peer-Reviewed Original ResearchConceptsInjection drug usersDate of seroconversionYear of seroconversionMedian timeRelative hazardGroups of IDUsDrug usersInfectious diseasesCohort of IDUsFirst positive HIV testClinic-based cohortSimilar median timeHIV disease progressionProspective cohort studyPositive HIV testInjection drug useCommunity-based cohortHIV-positive individualsInfectious disease deathsTime of seroconversionDrug use characteristicsTerms of ageProportion of womenALIVE studyCohort studyHIV prevalence and risk behaviors among new initiates into injection drug use over the age of 40 years old
Carneiro M, Fuller C, Doherty M, Vlahov D. HIV prevalence and risk behaviors among new initiates into injection drug use over the age of 40 years old. Drug And Alcohol Dependence 1999, 54: 83-86. PMID: 10101620, DOI: 10.1016/s0376-8716(98)00142-2.Peer-Reviewed Original ResearchConceptsInjection drug usersInjection drug useRisk behaviorsDrug usersDrug useCross-sectional studyRates of HIVHigh-risk behaviorsAge of initiationHIV infectionHIV prevalenceFirst injectionWide age rangeAverage ageNew initiatesHygiene practicesAge rangeAgeRecruitment techniquesInjectionYearsHIVInitiationInfectionPrevalence
1998
The role of needle exchange programs in HIV prevention.
Vlahov D, Junge B. The role of needle exchange programs in HIV prevention. Public Health Reports 1998, 113 Suppl 1: 75-80. PMID: 9722812, PMCID: PMC1307729.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusNeedle exchange programsCase-control studyNeedle exchangeHIV preventionMultiperson useNew Haven's needle exchange programDrug usersDrug useBlood-borne viral infectionsHepatitis C virus infectionSyringe-sharing behaviorsC virus infectionBlood-borne infectionsInjection drug useBlood-borne pathogensPossession of syringesSyringe trackingHCV infectionHepatitis BHIV seroincidenceHIV infectionImmunodeficiency syndromeHIV transmissionImmunodeficiency virus