1999
Comparison between a Whole Blood Interferon-γ Release Assay and Tuberculin Skin Testing for the Detection of Tuberculosis Infection among Patients at Risk for Tuberculosis Exposure
Kimura M, Converse P, Astemborski J, Rothel J, Vlahov D, Comstock G, Graham N, Chaisson R, Bishai W. Comparison between a Whole Blood Interferon-γ Release Assay and Tuberculin Skin Testing for the Detection of Tuberculosis Infection among Patients at Risk for Tuberculosis Exposure. The Journal Of Infectious Diseases 1999, 179: 1297-1300. PMID: 10191241, DOI: 10.1086/314707.Peer-Reviewed Original ResearchConceptsTuberculin skin testIFN-gamma releaseTuberculosis infectionWhole-Blood Interferon-γ Release AssayStandard tuberculin skin testInterferon-γ release assaysPercent agreementCulture-confirmed tuberculosisHIV-seropositive subjectsTuberculin skin testingHuman immunodeficiency virusInterferon-gamma releaseIntravenous drug usersSingle blood drawSeronegative patientsTuberculosis exposureSkin testingUninfected personsImmunodeficiency virusSkin testBlood drawUrban BaltimoreDrug usersRelease assaysFurther evaluation
1997
Comparison of a Tuberculin Interferon-γ Assay with the Tuberculin Skin Test in High-Risk Adults: Effect of Human Immunodeficiency Virus Infection
Converse P, Jones S, Astemborski J, Vlahov D, Graham N. Comparison of a Tuberculin Interferon-γ Assay with the Tuberculin Skin Test in High-Risk Adults: Effect of Human Immunodeficiency Virus Infection. The Journal Of Infectious Diseases 1997, 176: 144-150. PMID: 9207360, DOI: 10.1086/514016.Peer-Reviewed Original ResearchConceptsTuberculin skin testHuman immunodeficiency virus (HIV) infectionImmunodeficiency virus infectionSkin testVirus infectionIFN-gammaNegative tuberculin skin testPositive tuberculin skin testInterferon-γ AssayTST induration diameterWhole bloodHigh-risk adultsIntravenous drug usersMycobacterium tuberculosis exposureWhole blood IFN-gammaIFN-gamma responsesCutaneous anergyMitogen controlSeronegative subjectsTuberculosis exposureHIV infectionTuberculin reactivityWhole heparinized bloodInduration diameterDrug users