1996
Alcohol Use and T‐Lymphocyte Subsets among Injection Drug Users with HIV‐1 Infection: A Prospective Analysis
Crum R, Galai N, Cohn S, Celentano D, Vlahov D. Alcohol Use and T‐Lymphocyte Subsets among Injection Drug Users with HIV‐1 Infection: A Prospective Analysis. Alcohol Clinical And Experimental Research 1996, 20: 364-371. PMID: 8730231, DOI: 10.1111/j.1530-0277.1996.tb01654.x.Peer-Reviewed Original ResearchConceptsInjection drug usersCohort of IDUsT lymphocyte subsetsDrinks/weekHIV seroconversionAlcohol useYears postseroconversionDrug usersAlcohol categoriesHIV-positive injection drug usersCD8 absolute countsHIV-1 seroconvertersProgression of immunodeficiencyLevels of CD4Intravenous drug useT lymphocyte subpopulationsFirst prospective studyHIV-1 infectionTime of seroconversionSignificant differencesEarly intervention programsHIV infectionHIV progressionOutpatient clinicProspective study
1992
HIV-1 infection and intravenous drug use: longitudinal neuropsychological evaluation of asymptomatic subjects.
Selnes O, McArthur J, Royal W, Updike M, Nance-Sproson T, Concha M, Gordon B, Solomon L, Vlahov D. HIV-1 infection and intravenous drug use: longitudinal neuropsychological evaluation of asymptomatic subjects. Neurology 1992, 42: 1924-30. PMID: 1407574, DOI: 10.1212/wnl.42.10.1924.Peer-Reviewed Original ResearchConceptsIntravenous drug usersIntravenous drug useDrug usersHIV infectionSerostatus groupsHIV-seropositive intravenous drug usersDrug useHIV-1 infectionHigh-risk groupRoute of acquisitionLongitudinal neuropsychological evaluationCross-sectional comparisonPreexisting deficitAsymptomatic subjectsLongitudinal followAdditional cognitive impairmentPresymptomatic stageNeurocognitive abnormalitiesCognitive impairmentNeuropsychological evaluationNeuropsychological deficitsSame cohortBisexual menInfectionSignificant differences