1993
Elevated serum levels of neopterin but not β2-microglobulin in HIV-1-seronegative injecting drug users
Strickler H, Blanchard J, Vlahov D, Taylor E, Muñoz A, Nelson K, Margolick J. Elevated serum levels of neopterin but not β2-microglobulin in HIV-1-seronegative injecting drug users. AIDS 1993, 7: 361-368. PMID: 8471199, DOI: 10.1097/00002030-199303000-00009.Peer-Reviewed Original ResearchConceptsDrug useNeopterin levelsSerum levelsDrug usersSerum beta 2MBeta 2M levelsSerum beta 2M levelsMean neopterin levelsSerum neopterin levelsElevated serum levelsHIV-1 infectionCellular immune activationBeta 2MRisk factor variablesIntravenous Experience (ALIVE) studyM levelsMale IDUsSerum neopterinImmune activationProspective studyImmunocompetent cellsHIV-1Β2-microglobulinConsecutive daysNeopterin
1992
Prognostic indicators for development of AIDS among intravenous drug users.
Muñoz A, Vlahov D, Solomon L, Margolick J, Bareta J, Cohn S, Astemborski J, Nelson K. Prognostic indicators for development of AIDS among intravenous drug users. JAIDS Journal Of Acquired Immune Deficiency Syndromes 1992, 5: 694-700. PMID: 1613668.Peer-Reviewed Original ResearchConceptsCD4 cell countIntravenous drug usersClinical symptomsDrug usersCell countHigher CD4 cell countsHIV-1-related symptomsSeropositive intravenous drug usersPneumocystis carinii prophylaxisIntravenous drug useDevelopment of AIDSDose-response relationshipYear of enrollmentSerum neopterinLaboratory markersSerum betaPrognostic indicatorClinical evaluationAntiviral agentsRelative hazardDrug useSurvival analysisMultivariate analysisSignificant associationAIDS