Use of HIV Protease Inhibitors Is Associated with Left Ventricular Morphologic Changes and Diastolic Dysfunction
Meng Q, Lima J, Lai H, Vlahov D, Celentano D, Strathdee S, Nelson K, Tong W, Lai S. Use of HIV Protease Inhibitors Is Associated with Left Ventricular Morphologic Changes and Diastolic Dysfunction. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2002, 30: 306-310. DOI: 10.1097/01.qai.0000017995.56638.f8.Peer-Reviewed Original ResearchPosterior wall thicknessHIV infectionHigher interventricular septum thicknessHIV protease inhibitor therapyLeft ventricular systolic functionLV posterior wall thicknessEarly peak velocityLate peak velocitiesNon-PI groupVentricular systolic functionCardiac valve regurgitationProtease inhibitor therapyInterventricular septum thicknessLog-transformed durationPeak velocityHIV protease inhibitorsAntiretroviral therapyDiastolic dysfunctionPI therapyVascular complicationsAtrial dimensionSystolic functionInhibitor therapyLV hypertrophyValve regurgitation