1996
Effect of Mycobacterium tuberculosis on HIV replication. Role of immune activation.
Goletti D, Weissman D, Jackson R, Graham N, Vlahov D, Klein R, Munsiff S, Ortona L, Cauda R, Fauci A. Effect of Mycobacterium tuberculosis on HIV replication. Role of immune activation. The Journal Of Immunology 1996, 157: 1271-8. PMID: 8757635, DOI: 10.4049/jimmunol.157.3.1271.Peer-Reviewed Original ResearchConceptsHIV replicationMTB diseaseMycobacterium tuberculosisLymph node mononuclear cellsViral replicationCellular activationProtein derivative positivityPlasma viral loadAg-specific activationT cell-depleted lymphocytesPPD-negative donorsHIV diseaseHIV infectionAcute phaseViral loadImmune activationMononuclear cellsPPD positivityHealthy donorsHIV epidemicT cellsPrimary PBMCsHIV infection modelEpidemiology dataHIV
1994
Validation of the proposed World Health Organization staging system for HIV disease and infection in a cohort of intravenous drug users
Aylward R, Vlahov D, Muñoz A, Rapiti E. Validation of the proposed World Health Organization staging system for HIV disease and infection in a cohort of intravenous drug users. AIDS 1994, 8: 1129-1134. PMID: 7986411, DOI: 10.1097/00002030-199408000-00015.Peer-Reviewed Original ResearchConceptsIntravenous drug usersClinical stage 1Proportional hazards modelStaging systemProduct limit estimatesWorld Health OrganizationALIVE studyHIV diseaseHazards modelPopulation of IVDUWorld Health Organization (WHO) staging systemDrug usersCox proportional hazards modelStage 1WHO staging systemTime of progressionStage 2Index visitHIV seropositivityHIV-seropositivePrognostic utilityClinical stageClinical criteriaOriginal cohortClinical signs