Alginate microparticles loaded with basic fibroblast growth factor induce tissue coverage in a rat model of myelomeningocele
Farrelly JS, Bianchi AH, Ricciardi AS, Buzzelli GL, Ahle SL, Freedman-Weiss MR, Luks VL, Saltzman WM, Stitelman DH. Alginate microparticles loaded with basic fibroblast growth factor induce tissue coverage in a rat model of myelomeningocele. Journal Of Pediatric Surgery 2018, 54: 80-85. PMID: 30414695, DOI: 10.1016/j.jpedsurg.2018.10.031.Peer-Reviewed Original ResearchMeSH KeywordsAlginatesAmniotic FluidAnimalsBiocompatible MaterialsFemaleFetal TherapiesFibroblast Growth Factor 2MeningomyeloceleMinimally Invasive Surgical ProceduresPregnancyRatsConceptsSoft tissue coverageTissue coverageRat modelTime-dated pregnant ratsFree bFGFGrowth factorInjection of microparticlesBasic fibroblast growth factorFibroblast growth factorPregnant ratsPrenatal treatmentIntraamniotic injectionFetal myelomeningoceleMyelomeningoceleMMC coverageMMC defectsRetinoic acidBFGF