In-frame TCR δ gene rearrangements play a critical role in the αβ/γδ T cell lineage decision
Livak F, Petrie H, Crisps I, Schatz D. In-frame TCR δ gene rearrangements play a critical role in the αβ/γδ T cell lineage decision. Immunity 1995, 2: 617-627. PMID: 7796295, DOI: 10.1016/1074-7613(95)90006-3.Peer-Reviewed Original ResearchConceptsT cell lineage decisionsCell lineage decisionsLineage decisionsRandom gene rearrangementsSouthern blot analysisT cell receptor complexCell receptor complexGene rearrangementsDelta locusLocus sequenceGamma delta lineageReceptor complexT cell receptorBlot analysisDistinct precursorsCommon precursorCell receptorCritical roleDelta rearrangementsDelta lineageRearrangementΔ gene rearrangementAlpha betaT cellsGamma delta T-cell receptor