Regulation of affect by the lateral septum: implications for neuropsychiatry
Sheehan T, Chambers R, Russell D. Regulation of affect by the lateral septum: implications for neuropsychiatry. Brain Research Reviews 2004, 46: 71-117. PMID: 15297155, DOI: 10.1016/j.brainresrev.2004.04.009.Peer-Reviewed Original ResearchConceptsLateral septumAdministration of antipsychoticsDepression-like phenotypeMesocorticolimbic dopamine systemMidbrain dopamine neuronsPsychotic spectrum disordersLS neuronsDopamine neuronsBlunted activityL-neuronsDopamine systemPsychiatric conditionsHippocampal inputsVentral striatumBest treatmentNeuronsNeural activityBehavioral manifestationsSubstantial evidenceAffective functionsSeptumSpectrum disorderMolecular studiesRegulation of affectCritical role