2012
Quantitative assessment of invasive mena isoforms (Menacalc) as an independent prognostic marker in breast cancer
Agarwal S, Gertler FB, Balsamo M, Condeelis JS, Camp RL, Xue X, Lin J, Rohan TE, Rimm DL. Quantitative assessment of invasive mena isoforms (Menacalc) as an independent prognostic marker in breast cancer. Breast Cancer Research 2012, 14: r124. PMID: 22971274, PMCID: PMC3962029, DOI: 10.1186/bcr3318.Peer-Reviewed Original ResearchConceptsBreast cancer cohortBreast cancerPoor outcomeTumor cellsCancer cohortPoor disease-specific survivalDisease-specific deathDisease-specific survivalBreast cancer patientsIndependent prognostic markerIndependent breast cancer cohortsNon-invasive tumor cellsInvasive tumor cellsReceptor statusNode statusTumor sizeCancer patientsPrognostic markerSignificant associationCohortCancerIsoform expressionPatientsMetastasisOutcomes
1995
Autoantibodies specific for villin found in patients with colon cancer and other colitides
Rimm D, Holland T, Morrow J, Anderson J. Autoantibodies specific for villin found in patients with colon cancer and other colitides. Digestive Diseases And Sciences 1995, 40: 389-395. PMID: 7851204, DOI: 10.1007/bf02065426.Peer-Reviewed Original ResearchConceptsColon cancerActive autoimmune responseSpecific gastrointestinal diseasesLevels of autoantibodiesColon cancer patients´ seraCancer patient seraIntestinal epithelial cellsCryptic antigensAutoimmune responseGastrointestinal pathologyColonic diseaseGastrointestinal diseasesPatient seraNormal controlsPathological significanceWestern blotDisease statesEpithelial cellsNoninvasive approachUnique noninvasive approachAntibodiesAutoantibodiesBrush borderPatientsCancer
1991
Analysis of cDNA clones for Acanthamoeba profilin‐I and profilin‐II shows end to end homology with vertebrate profilins and a small family of profilin genes
Pollard T, Rimm D. Analysis of cDNA clones for Acanthamoeba profilin‐I and profilin‐II shows end to end homology with vertebrate profilins and a small family of profilin genes. Cytoskeleton 1991, 20: 169-177. PMID: 1751969, DOI: 10.1002/cm.970200209.Peer-Reviewed Original ResearchConceptsProfilin IIDNA sequencesProtein sequencesAcanthamoeba profilinGenomic DNA fragmentsFull-length cDNAFamily of proteinsProfilin geneAncestral precursorDifferent phylaInvariant residuesAdditional genesCDNA clonesLength cDNAConservative substitutionsPairwise identityDNA fragmentsSouthern blotNorthern blotGenesProfilinAmino acidsSmall familyCDNAConsiderable divergence