2003
Detection of chromosomal instability in paired breast surgery and ductal lavage specimens by interphase fluorescence in situ hybridization.
King BL, Tsai SC, Gryga ME, D'Aquila TG, Seelig SA, Morrison LE, Jacobson KK, Legator MS, Ward DC, Rimm DL, Phillips RF. Detection of chromosomal instability in paired breast surgery and ductal lavage specimens by interphase fluorescence in situ hybridization. Clinical Cancer Research 2003, 9: 1509-16. PMID: 12684427.Peer-Reviewed Original ResearchConceptsDuctal lavageMalignant casesBenign casesBreast lesionsBreast cellsInvasive breast cancerInterphase fluorescenceBreast cancer progressionAbnormal cytologyLavage cellsSitu hybridizationBreast surgeryBreast cancerEarly neoplasiaConventional cytologyLavageGenetic abnormalitiesCancer progressionNew modalityNumeric changesSitu hybridization analysisSurgeryLesionsCytologyAbnormalities
2002
Immunocytochemical analysis of breast cells obtained by ductal lavage
King BL, Crisi GM, Tsai SC, Haffty BG, Phillips RF, Rimm DL. Immunocytochemical analysis of breast cells obtained by ductal lavage. Cancer 2002, 96: 244-249. PMID: 12209667, DOI: 10.1002/cncr.10719.Peer-Reviewed Original ResearchConceptsDuctal lavageBreast fluidFoam cellsEpithelial cellsHistiocytic originSpecific antibodiesMammary epithelial cellsImmunocytochemical analysisBreast cellsCD68 monoclonal antibodyAE1/AE3Macrophage-specific antibodiesFemale patientsLavage cellsCytologic abnormalitiesCD68 antibodyMammary epithelial originLavage samplesMedian numberBreast ductsLavage specimensDuctal systemLavagePositive stainingImmunocytochemical staining