Utility of CD8 score by automated quantitative image analysis in head and neck squamous cell carcinoma
Hartman DJ, Ahmad F, Ferris R, Rimm D, Pantanowitz L. Utility of CD8 score by automated quantitative image analysis in head and neck squamous cell carcinoma. Oral Oncology 2018, 86: 278-287. PMID: 30409313, PMCID: PMC6260977, DOI: 10.1016/j.oraloncology.2018.10.005.Peer-Reviewed Original ResearchConceptsCD8 T cellsImmune cell densityOropharyngeal HNSCCT cellsNeck squamous cell carcinomaCD8 cell densityImmune cell infiltratesSquamous cell carcinomaWhole tissue sectionsEntire tumor sectionHPV infectionMedian survivalCell infiltrateHNSCC patientsCell carcinomaHNSCC casesClinicopathologic parametersOnly predictorTumor sectionsBetter outcomesClinical practiceTumor microenvironmentCell densityClinical validationCells/