2005
Patterns of reduced nipple aspirate fluid production and ductal lavage cellularity in women at high risk for breast cancer
Higgins SA, Matloff ET, Rimm DL, Dziura J, Haffty BG, King BL. Patterns of reduced nipple aspirate fluid production and ductal lavage cellularity in women at high risk for breast cancer. Breast Cancer Research 2005, 7: r1017. PMID: 16280052, PMCID: PMC1410733, DOI: 10.1186/bcr1335.Peer-Reviewed Original ResearchConceptsHigh-risk womenFluid-yielding ductsPrevious multicenter trialsMulticenter trialBreast cancerDuctal lavageLavage cellularityPresent seriesNAF productionSelective estrogen receptor modulatorsRisk-reducing therapiesRisk reduction therapyBRCA germline mutationsEstrogen receptor modulatorsBRCA-positive womenBreast cancer developmentEvaluation of abnormalitiesPostmenopausal statusHealthy womenBreast fluidIntraductal approachReceptor modulatorsRelative riskDuctal orificeReduction therapy
2002
Immunocytochemical analysis of breast cells obtained by ductal lavage
King BL, Crisi GM, Tsai SC, Haffty BG, Phillips RF, Rimm DL. Immunocytochemical analysis of breast cells obtained by ductal lavage. Cancer 2002, 96: 244-249. PMID: 12209667, DOI: 10.1002/cncr.10719.Peer-Reviewed Original ResearchConceptsDuctal lavageBreast fluidFoam cellsEpithelial cellsHistiocytic originSpecific antibodiesMammary epithelial cellsImmunocytochemical analysisBreast cellsCD68 monoclonal antibodyAE1/AE3Macrophage-specific antibodiesFemale patientsLavage cellsCytologic abnormalitiesCD68 antibodyMammary epithelial originLavage samplesMedian numberBreast ductsLavage specimensDuctal systemLavagePositive stainingImmunocytochemical staining