195. Reducing Time to Optimal Antimicrobial Therapy (OAT) for Bloodstream Infections (BSI) due to Gram Positive Cocci (GPC) in Chains Using Rapid Diagnostics Paired with Antimicrobial Stewardship (ASP) Efforts
K J, McSweeney T, McManus D, Davis M, Merwede J, Peaper D, Topal J. 195. Reducing Time to Optimal Antimicrobial Therapy (OAT) for Bloodstream Infections (BSI) due to Gram Positive Cocci (GPC) in Chains Using Rapid Diagnostics Paired with Antimicrobial Stewardship (ASP) Efforts. Open Forum Infectious Diseases 2022, 9: ofac492.273. PMCID: PMC9752006, DOI: 10.1093/ofid/ofac492.273.Peer-Reviewed Original ResearchOptimal antimicrobial therapyLength of stayGram-positive cocciBloodstream infectionsASP recommendationsHigher Charlson comorbidity indexMedian LOSCharlson Comorbidity IndexPost-implementation cohortPre-implementation cohortPrimary study endpointRetrospective chart reviewRapid diagnosticsPositive Gram stainYears of ageAntimicrobial stewardship effortsASP interventionsComorbidity indexPrimary endpointBaseline demographicsChart reviewSecondary outcomesStudy endpointPolymicrobial infectionsAntimicrobial therapy