2007
Cost-effectiveness of omalizumab in adults with severe asthma: Results from the Asthma Policy Model
Wu AC, Paltiel AD, Kuntz KM, Weiss ST, Fuhlbrigge AL. Cost-effectiveness of omalizumab in adults with severe asthma: Results from the Asthma Policy Model. Journal Of Allergy And Clinical Immunology 2007, 120: 1146-1152. PMID: 17904628, PMCID: PMC3476046, DOI: 10.1016/j.jaci.2007.07.055.Peer-Reviewed Original ResearchConceptsQuality-adjusted life yearsCost-effectiveness ratioSevere asthmaEvent ratesSevere allergic asthmaQuality-adjusted monthsAllergic asthmaMost patientsAlternative medicationsHigher acquisition costUS FoodAsthmaDrug AdministrationLife yearsPatientsIncremental costDisease managementOmalizumabCost-effective optionTreatmentAcquisition costsEconomic outcomesCorticosteroidsMedicationsClinicians
2006
Forced Expiratory Volume in 1 Second Percentage Improves the Classification of Severity Among Children With Asthma
Fuhlbrigge AL, Weiss ST, Kuntz KM, Paltiel AD. Forced Expiratory Volume in 1 Second Percentage Improves the Classification of Severity Among Children With Asthma. Pediatrics 2006, 118: e347-e355. PMID: 16864642, DOI: 10.1542/peds.2005-2962.Peer-Reviewed Original ResearchMeSH KeywordsAlbuterolAnti-Asthmatic AgentsAsthmaBronchial Provocation TestsBronchodilator AgentsBudesonideChildChild, PreschoolCohort StudiesDouble-Blind MethodEmergency Service, HospitalEthnicityFemaleFollow-Up StudiesForced Expiratory VolumeHospitalizationHumansMaleMethacholine ChlorideModels, TheoreticalMulticenter Studies as TopicNedocromilRandomized Controlled Trials as TopicRiskSeverity of Illness IndexSpirometryTreatment OutcomeConceptsSerious asthma exacerbationsImportant clinical outcomesHealth care utilizationPrebronchodilator FEV1Asthma exacerbationsAsthma symptomsExpiratory volumeCare utilizationClinical outcomesSecond percentageAsthma health statusAsthma severity classificationAsthma-related eventsChildhood Asthma Management ProgramEpisode-free daysNational Asthma EducationAsthma-related hospitalizationsPrevention Program guidelinesMean symptom scoreAsthma Management ProgramFuture adverse eventsOutcomes of interestMultivariate regression analysisPopulation of childrenClassification of severity
2002
A novel approach to defining the relationship between lung function and symptom status in asthma
Kuntz KM, Kitch BT, Fuhlbrigge AL, Paltiel AD, Weiss ST. A novel approach to defining the relationship between lung function and symptom status in asthma. Journal Of Clinical Epidemiology 2002, 55: 11-18. PMID: 11781117, DOI: 10.1016/s0895-4356(01)00412-7.Peer-Reviewed Original ResearchMeSH KeywordsAdultAsthmaClinical Trials as TopicForced Expiratory VolumeHumansLinear ModelsPredictive Value of TestsSeverity of Illness IndexConceptsAsthma-related symptomsLung functionMean lung functionAverage baseline valuePopulation-wide basisExpiratory volumeSymptom daysSymptom scoresNighttime awakeningsSymptom statusClinical trialsMean changeBaseline valuesLinear regression analysisSymptomsRegression analysisNegative associationOverall improvementAssociationAsthmaConsistent relationshipTrials