2020
Lysis of cold‐storage‐induced microvascular obstructions for ex vivo revitalization of marginal human kidneys
DiRito JR, Hosgood SA, Reschke M, Albert C, Bracaglia LG, Ferdinand JR, Stewart BJ, Edwards CM, Vaish AG, Thiru S, Mulligan DC, Haakinson DJ, Clatworthy MR, Saltzman WM, Pober JS, Nicholson ML, Tietjen GT. Lysis of cold‐storage‐induced microvascular obstructions for ex vivo revitalization of marginal human kidneys. American Journal Of Transplantation 2020, 21: 161-173. PMID: 32627324, PMCID: PMC7775334, DOI: 10.1111/ajt.16148.Peer-Reviewed Original ResearchConceptsNormothermic machine perfusionHuman kidneyMicrovascular obstructionMarginal organsHigh-risk donorsSevere organ shortageLikelihood of complicationsMicrovascular blood flowAccumulation of fibrinogenCold storage injuryTissue plasminogen activatorImmediate translational potentialMicrovascular pluggingRenal functionRenal injuryMachine perfusionTubular epitheliumBlood flowIntravascular releaseOrgan shortagePhysiologic impactKidneyTranslational potentialPlasminogen activatorVivo assessment
2012
Single Center Review of Seroconversion Rate and Clinical Outcomes of Kidney Transplant Recipients from Center for Disease Control (CDC) High Risk Donors
Bodner J, Katariya N, Hewitt W, Moss A, Mulligan D, Heilman R, Chakkera H, Hamawi K, Khamash H, Beck G, Reddy K. Single Center Review of Seroconversion Rate and Clinical Outcomes of Kidney Transplant Recipients from Center for Disease Control (CDC) High Risk Donors. Transplantation 2012, 94: 141. DOI: 10.1097/00007890-201211271-00260.Peer-Reviewed Original Research