2022
Experimental VX2 Rabbit Liver Tumor Model in Carbon Tetrachloride–Induced Cirrhosis of the Liver
Santana J, Shewarega A, Nam D, Kahl V, Madoff D, Zhang X, Chapiro J. Experimental VX2 Rabbit Liver Tumor Model in Carbon Tetrachloride–Induced Cirrhosis of the Liver. Journal Of Vascular And Interventional Radiology 2022, 34: 404-408.e1. PMID: 36473611, PMCID: PMC11037556, DOI: 10.1016/j.jvir.2022.11.026.Peer-Reviewed Original ResearchConceptsLiver cirrhosisMale New Zealand white rabbitsRabbit liver tumor modelCirrhotic liver backgroundReproducible tumor growthVX2 liver cancerLeft hepatic lobeNew Zealand white rabbitsDuration of treatmentLiver tumor modelCross-sectional imagingVX2 rabbit liver tumor modelZealand white rabbitsHepatic lobeHistopathological evaluationMajor underlying factorHepatic tumorsIntragastric administrationHepatocellular carcinomaLiver tumorsLiver cancerCirrhosisUnmet needTumor growthVX2 tumors
2013
Evaluation of liver fibrosis and hepatic venous pressure gradient with MR elastography in a novel swine model of cirrhosis
Huang SY, Abdelsalam ME, Harmoush S, Ensor JE, Chetta JA, Hwang KP, Stafford RJ, Madoff DC, Avritscher R. Evaluation of liver fibrosis and hepatic venous pressure gradient with MR elastography in a novel swine model of cirrhosis. Journal Of Magnetic Resonance Imaging 2013, 39: 590-597. PMID: 24532376, DOI: 10.1002/jmri.24189.Peer-Reviewed Original ResearchConceptsHepatic venous pressure gradientVenous pressure gradientLiver stiffnessLiver fibrosisSwine modelExperimental animalsMR elastographyHigher liver stiffnessMean fibrosis scoreNovel swine modelReliable noninvasive techniquePositive correlationLiver cirrhosisTransarterial embolizationFibrosis scoreCirrhosisFibrosisExperimental swineSignificant positive correlationNoninvasive technique
2011
Indications and Contraindications for Portal Vein Embolization
Madoff D, Vauthey J. Indications and Contraindications for Portal Vein Embolization. 2011, 123-128. DOI: 10.1007/978-1-84882-122-4_13.Peer-Reviewed Original ResearchPortal vein embolizationTotal liver volumeVein embolizationUse of PVEFuture liver remnant volumeLiver remnant volumePatient body sizeFLR volumePerioperative outcomesPatient ageSurgical candidatesLiver diseaseRemnant volumeSurgical interventionLiver volumeCT volumetryHealthy liverParticular patientPatientsContraindicationsEmbolizationAgeMultiple factorsCirrhosisComorbidities