Yttrium 90 Resin Microspheres for the Treatment of Unresectable Colorectal Hepatic Metastases after Failure of Multiple Chemotherapy Regimens: Preliminary Results
Murthy R, Xiong H, Nunez R, Cohen AC, Barron B, Szklaruk J, Madoff DC, Gupta S, Wallace MJ, Ahrar K, Hicks ME. Yttrium 90 Resin Microspheres for the Treatment of Unresectable Colorectal Hepatic Metastases after Failure of Multiple Chemotherapy Regimens: Preliminary Results. Journal Of Vascular And Interventional Radiology 2005, 16: 937-945. PMID: 16002501, DOI: 10.1097/01.rvi.0000161142.12822.66.Peer-Reviewed Original ResearchConceptsUnresectable colorectal hepatic metastasesColorectal hepatic metastasesHepatic metastasesSIR-SpheresMultiple chemotherapySingle infusionPrescribed doseYttrium-90 resin microspheresEmbolic arterial occlusionHepatic metastatic diseaseMultiple chemotherapy regimensLiver-directed therapiesCarcinoembryonic antigen levelYttrium-90 microspheresCompletion of treatmentMedian survival timeHepatic tumor volumeBilobar diseaseIntrahepatic progressionRadiologic responseUnilobar diseaseAdvanced diseaseChemotherapy regimenChemotherapy regimensIntraarterial chemotherapy