2007
Pilot study of regional, hepatic intra‐arterial paclitaxel in patients with breast carcinoma metastatic to the liver
Camacho LH, Kurzrock R, Cheung A, Barber DF, Gupta S, Madoff DC, Wallace MJ, Kim EE, Curley SA, Hortobagyi GN, Mavligit G. Pilot study of regional, hepatic intra‐arterial paclitaxel in patients with breast carcinoma metastatic to the liver. Cancer 2007, 109: 2190-2196. PMID: 17464952, DOI: 10.1002/cncr.22672.Peer-Reviewed Original ResearchConceptsDominant liver metastasisBreast carcinomaTaxane exposureLiver metastasesAntitumor activityCommon treatment-related toxicitiesHepatic intra-arterial therapyPatient underwent liver resectionCourses of paclitaxelUnderwent liver resectionMean patient ageTreatment-related toxicityHepatic arterial infusionIntra-arterial therapyProcedure-related complicationsBreast carcinoma metastaticMetastatic breast carcinomaIntra-arterial catheterPercutaneous transfemoral approachTime of treatmentHepatic infusionStable diseaseCarcinoma metastaticPaclitaxel therapyTaxane therapy
2006
Pilot study of regional hepatic intra-arterial (HIA) paclitaxel in patients (Pts) with breast carcinoma metastatic to the liver
Mavligit G, Kurzrock R, Cheung A, Gupta S, Madoff D, Wallace M, Kim E, Curley S, Hortobagyi G, Camacho L. Pilot study of regional hepatic intra-arterial (HIA) paclitaxel in patients (Pts) with breast carcinoma metastatic to the liver. Journal Of Clinical Oncology 2006, 24: 10626-10626. DOI: 10.1200/jco.2006.24.18_suppl.10626.Peer-Reviewed Original ResearchAnti-tumor activityBreast carcinomaTaxane exposureDominant liver metastasisHepatic arterial therapyPrevious treatment regimensUnderwent liver resectionMean hospital stayBreast carcinoma metastaticMetastatic breast carcinomaIntra-arterial catheterPercutaneous transfemoral approachGood anti-tumor activityMost common treatmentTime of treatmentAdjuvant regimensArterial therapyCarcinoma metastaticDisease stabilizationHospital stayPaclitaxel therapyTaxane therapyLiver involvementLiver metastasesLiver resection