B‐cell lymphoma in severe combined immunodeficiency not associated with the Epstein–Barr virus
Garcia C, Brown N, Schreck R, Stiehm E, Hudnall S. B‐cell lymphoma in severe combined immunodeficiency not associated with the Epstein–Barr virus. Cancer 1987, 60: 2941-2947. PMID: 2824020, DOI: 10.1002/1097-0142(19871215)60:12<2941::aid-cncr2820601216>3.0.co;2-a.Peer-Reviewed Original ResearchConceptsEpstein-Barr virus nuclear antigenB-cell lymphomaB-cell lymphoproliferative disordersEBV DNASevere combined immunodeficiencyLymphoproliferative disordersMalignant B-cell lymphomaEBV DNA probePrevention of EBVImmunoglobulin heavy chain gene rearrangementB-cell lymphoproliferationEpstein-Barr virusClonal B-cell lymphomaGene rearrangementsHeavy chain gene rearrangementClonal Ig gene rearrangementsChain gene rearrangementAntiviral chemoprophylaxisTransplant patientsSuch prophylaxisImmunodeficient patientsTumor cell DNAAnticomplement immunofluorescenceSitu cytohybridizationPatients