Methylenetetrahydrofolate reductase (MTHFR): The incidence of mutations C677T and A1298C in the Ashkenazi Jewish population
Rady P, Tyring S, Hudnall S, Vargas T, Kellner L, Nitowsky H, Matalon R. Methylenetetrahydrofolate reductase (MTHFR): The incidence of mutations C677T and A1298C in the Ashkenazi Jewish population. American Journal Of Medical Genetics 1999, 86: 380-384. PMID: 10494095, DOI: 10.1002/(sici)1096-8628(19991008)86:4<380::aid-ajmg13>3.0.co;2-9.Peer-Reviewed Original ResearchConceptsMutation C677TC677TMethylenetetrahydrofolate reductaseVascular diseaseA1298C mutationA1298C allelesAshkenazi Jewish populationSpina bifidaRisk mutationsC677T alleleC677T mutationAshkenazi JewsHealthy individualsT alleleMTHFR geneJewish individualsA1298CHealthy Jewish individualsDNA samplesCommon mutationsFurther studiesT mutationDiseaseJewish populationBifida