2023
Computational phenotypes for patients with opioid-related disorders presenting to the emergency department
Taylor R, Gilson A, Schulz W, Lopez K, Young P, Pandya S, Coppi A, Chartash D, Fiellin D, D’Onofrio G. Computational phenotypes for patients with opioid-related disorders presenting to the emergency department. PLOS ONE 2023, 18: e0291572. PMID: 37713393, PMCID: PMC10503758, DOI: 10.1371/journal.pone.0291572.Peer-Reviewed Original ResearchMeSH KeywordsAnalgesics, OpioidEmergency Service, HospitalHumansOpioid-Related DisordersPhenotypeRetrospective StudiesConceptsSubstance use disordersUse disordersED visitsPatient presentationCarlson comorbidity indexOpioid-related diagnosesOpioid-related disordersOne-year survivalRate of medicationOpioid use disorderElectronic health record dataPatient-oriented outcomesYears of ageHealth record dataChronic substance use disordersED returnComorbidity indexAcute overdoseMedical managementClinical entityRetrospective studyEmergency departmentChronic conditionsInclusion criteriaUnique cohort
2021
Analysis of Health Trajectories Leading to Adverse Opioid-Related Events.
Gilson AS, Chartash D, Chang D, Hawk K, D'Onofrio G, Haimovich AD, Fiellin DA, Taylor RA. Analysis of Health Trajectories Leading to Adverse Opioid-Related Events. AMIA Joint Summits On Translational Science Proceedings 2021, 2021: 248-256. PMID: 34457139, PMCID: PMC8378649.Peer-Reviewed Original ResearchConceptsRelative riskHealth trajectoriesHealth service eventsPatient risk factorsMental health diagnosesHigher relative riskLargest relative riskCombination of diagnosisViral hepatitisPatient cohortRisk factorsRisk-based interventionsMental health codesNatural historyPatient diagnosisHealth diagnosisDiagnosisTherapy agentsPotential causal mechanismsRiskAverage populationAOEHealth CodeHepatitisOpioids