1992
Atypical presynaptic alpha-adrenoceptor modulation of neurally-mediated cholinergic responses in guinea-pig tracheal smooth muscle
Thompson D, Diamond L, Altiere R. Atypical presynaptic alpha-adrenoceptor modulation of neurally-mediated cholinergic responses in guinea-pig tracheal smooth muscle. Pulmonary Pharmacology & Therapeutics 1992, 5: 251-255. PMID: 1477481, DOI: 10.1016/0952-0600(92)90067-q.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsClonidineDrug InteractionsGuinea PigsMaleMuscle ContractionMuscle, SmoothNorepinephrinePrazosinTracheaYohimbineConceptsGuinea pig tracheaGuinea pig tracheal smooth muscleInhibitory actionAlpha-adrenoceptor modulationCholinergic excitatory nervesCholinergic excitatory responsesIntermittent nerve stimulationAlpha-adrenoceptor agonistsPresynaptic inhibitory actionPresynaptic inhibitory effectAction of norepinephrineUse of norepinephrineNorepinephrine-induced inhibitionTracheal smooth musclePretreatment of tissuesConcentration-dependent inhibitionConcentration-dependent mannerCholinergic contractionsPresynaptic alphaCholinergic nervesExcitatory nervesNerve stimulationCholinergic responsesExcitatory responsesSmooth muscle
1988
The effects of antagonists of vasoactive intestinal peptide on nonadrenergic noncholinergic inhibitory responses in feline airways
Thompson D, Altiere R, Diamond L. The effects of antagonists of vasoactive intestinal peptide on nonadrenergic noncholinergic inhibitory responses in feline airways. Peptides 1988, 9: 443-447. PMID: 3131749, DOI: 10.1016/0196-9781(88)90284-7.Peer-Reviewed Original ResearchConceptsIntrapulmonary bronchiInhibitory responsesNonadrenergic noncholinergic inhibitory responsesEffective competitive antagonistNANC inhibitory responsesNANC relaxation responsesNoncholinergic inhibitory responsesRole of VIPVIP receptor antagonistVasoactive intestinal peptideEffects of antagonistsHigher VIP concentrationsVIP concentrationsVIP antagonistFeline airwaysIntestinal peptideReceptor antagonistVIP receptorsCompetitive antagonistNervous stimulationAntagonistRelaxation responseVIPGRFResponse