Localized Mucosal Response to Intranasal Live Attenuated Influenza Vaccine in Adults
Barría MI, Garrido JL, Stein C, Scher E, Ge Y, Engel SM, Kraus TA, Banach D, Moran TM. Localized Mucosal Response to Intranasal Live Attenuated Influenza Vaccine in Adults. The Journal Of Infectious Diseases 2012, 207: 115-124. PMID: 23087433, PMCID: PMC3571238, DOI: 10.1093/infdis/jis641.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, IntranasalAdolescentAdultAnimalsAntibodies, ViralCohort StudiesCytokinesDogsFemaleHemagglutinin Glycoproteins, Influenza VirusHumansImmunity, MucosalImmunoglobulin AInfluenza A Virus, H1N1 SubtypeInfluenza A Virus, H3N2 SubtypeInfluenza B virusInfluenza VaccinesInfluenza, HumanMadin Darby Canine Kidney CellsMaleMiddle AgedNasal Lavage FluidVaccinationVaccines, AttenuatedVaccines, InactivatedYoung AdultConceptsNasal washesInfluenza vaccineMajor public health burdenSerum G-CSF levelsLive attenuated influenza vaccineAttenuated influenza vaccineImmunoglobulin A (IgA) antibodiesLow serum levelsGranulocyte colony-stimulating factorImmunoglobulin G levelsInfluenza virus infectionG-CSF levelsPublic health burdenColony-stimulating factorInterferon response genesMucosal responsesSerum levelsMucosal IgAIP-10Local inflammationAntibody responseTrivalent vaccineA antibodiesHealth burdenLocalized inflammation