Tubedown Expression Correlates with the Differentiation Status and Aggressiveness of Neuroblastic Tumors
Martin DT, Gendron RL, Jarzembowski JA, Perry A, Collins MH, Pushpanathan C, Miskiewicz E, Castle VP, Paradis H. Tubedown Expression Correlates with the Differentiation Status and Aggressiveness of Neuroblastic Tumors. Clinical Cancer Research 2007, 13: 1480-1487. PMID: 17332292, DOI: 10.1158/1078-0432.ccr-06-1716.Peer-Reviewed Original ResearchConceptsNeuroblastic tumorsPrognostic factorsDifferentiation statusIndependent prognostic factorRisk group stratificationHigh-risk groupNew prognostic factorsNormal adrenal tissueRetinoic acid-induced neuronal differentiationNeuroblastoma cell linesUnfavorable histopathologyPoor outcomeNeuroblastoma patientsAdrenal tissueGroup stratificationTumor subsetsAdvanced stageDifferentiation responseFavorable histopathologyTumorsNeuroblastoma cellsExpression correlatesWestern blotWestern blottingMonoclonal antibodies