Response to varying the nicotine content of cigarettes in vulnerable populations: an initial experimental examination of acute effects
Higgins S, Heil S, Sigmon S, Tidey J, Gaalema D, Stitzer M, Durand H, Bunn J, Priest J, Arger C, Miller M, Bergeria C, Davis D, Streck J, Zvorsky I, Redner R, Vandrey R, Pacek L. Response to varying the nicotine content of cigarettes in vulnerable populations: an initial experimental examination of acute effects. Psychopharmacology 2016, 234: 89-98. PMID: 27714427, PMCID: PMC5203959, DOI: 10.1007/s00213-016-4438-z.Peer-Reviewed Original ResearchConceptsNicotine withdrawalSmoking topographyVulnerable populationsLow nicotine content cigarettesConcurrent choice testingNicotine contentDouble-blind conditionsOpioid-dependent individualsNicotine content cigarettesResultsNo significant differencesDaily cigarette smokersBrief smoking abstinenceRationaleThe purposeCigarette smokersCompensatory smokingSmoking abstinenceReproductive ageAcute effectsContent cigarettesUntoward effectsAffective disordersLow dosesResearch cigarettesDisadvantaged womenDependence potential