2024
Changes in Weight Among Individuals With Psychiatric Conditions or Socioeconomic Disadvantage Assigned to Smoke Very Low Nicotine Content Cigarettes
Harfmann R, Heil S, Bunn J, Snell L, Tidey J, Sigmon S, Gaalema D, Lee D, Streck J, Bergeria C, Davis D, Plucinski S, Higgins S. Changes in Weight Among Individuals With Psychiatric Conditions or Socioeconomic Disadvantage Assigned to Smoke Very Low Nicotine Content Cigarettes. Experimental And Clinical Psychopharmacology 2024, 32: 181-188. PMID: 38236223, DOI: 10.1037/pha0000700.Peer-Reviewed Original ResearchOpioid use disorderNicotine reduction policyAffective disordersSocioeconomically disadvantaged womenHigh dosesShort-term adverse consequencesNicotine abstinenceNicotine doseEffects of cigarettesPsychiatric conditionsUse disorderNicotine exposureWeekly assessmentsNicotineGroup of individualsRandomized controlled trialsDisordersAssessment of weightDisadvantaged womenFunction of doseCombination groupControlled trialsDoseSecondary analysisAdverse consequences
2021
Effects of Reduced Nicotine Content Cigarettes on Fractional Exhaled Nitric Oxide and Self-Reported Respiratory Health Outcomes Among Smokers With Psychiatric Conditions or Socioeconomic Disadvantage
Oliver A, DeSarno M, Irvin C, Kaminsky D, Tidey J, Sigmon S, Heil S, Gaalema D, Lee D, Bunn J, Davis D, Streck J, Gallagher T, Higgins S. Effects of Reduced Nicotine Content Cigarettes on Fractional Exhaled Nitric Oxide and Self-Reported Respiratory Health Outcomes Among Smokers With Psychiatric Conditions or Socioeconomic Disadvantage. Nicotine & Tobacco Research 2021, 24: 135-140. PMID: 34255068, PMCID: PMC8826384, DOI: 10.1093/ntr/ntab145.Peer-Reviewed Original ResearchConceptsOpioid use disorderRespiratory health questionnaireFeNO levelsAffective disordersSocioeconomic disadvantageContent cigarettesEpithelial healthHealth outcomesSignificant dose-related changesReduced nicotine content cigarettesNicotine contentNitric oxideAssociations of FeNOHealthy respiratory systemHigher FeNO levelsSmoking-related decreaseSmoking-related reductionRespiratory health outcomesDose-related changesCigarette nicotine contentNicotine content cigarettesAdverse health outcomesAdult daily smokersCombustible tobacco useFeNO changes
2018
Reduced Nicotine Content Cigarettes and Cannabis Use in Vulnerable Populations
Parker M, Streck J, Bergeria C, Bunn J, Gaalema D, Davis D, Barrows A, Sigmon S, Tidey J, Heil S, Higgins S. Reduced Nicotine Content Cigarettes and Cannabis Use in Vulnerable Populations. Tobacco Regulatory Science 2018, 4: 84-91. PMID: 30417034, PMCID: PMC6219758, DOI: 10.18001/trs.4.5.8.Peer-Reviewed Original ResearchNicotine content cigarettesCarbon monoxide boostSmoking topographyContent cigarettesCannabis usersCannabis useConcurrent choice testingCo-morbid conditionsVulnerable populationsConcurrent affective disorderMore rapid declineRespiratory tract sensationsSymptom durationRecent cannabis useSmoking satisfactionOpioid dependenceNicotine dosesTobacco withdrawalNicotine doseAdult smokersAcute responseAffective disordersSociodemographic characteristicsSecondary analysisModerate response
2016
Response to varying the nicotine content of cigarettes in vulnerable populations: an initial experimental examination of acute effects
Higgins S, Heil S, Sigmon S, Tidey J, Gaalema D, Stitzer M, Durand H, Bunn J, Priest J, Arger C, Miller M, Bergeria C, Davis D, Streck J, Zvorsky I, Redner R, Vandrey R, Pacek L. Response to varying the nicotine content of cigarettes in vulnerable populations: an initial experimental examination of acute effects. Psychopharmacology 2016, 234: 89-98. PMID: 27714427, PMCID: PMC5203959, DOI: 10.1007/s00213-016-4438-z.Peer-Reviewed Original ResearchConceptsNicotine withdrawalSmoking topographyVulnerable populationsLow nicotine content cigarettesConcurrent choice testingNicotine contentDouble-blind conditionsOpioid-dependent individualsNicotine content cigarettesResultsNo significant differencesDaily cigarette smokersBrief smoking abstinenceRationaleThe purposeCigarette smokersCompensatory smokingSmoking abstinenceReproductive ageAcute effectsContent cigarettesUntoward effectsAffective disordersLow dosesResearch cigarettesDisadvantaged womenDependence potential