Immortalized GnRH Neurons Express Large-Conductance Calcium-Activated Potassium Channels
Spergel D, Catt K, Rojas E. Immortalized GnRH Neurons Express Large-Conductance Calcium-Activated Potassium Channels. Neuroendocrinology 1996, 63: 101-111. PMID: 9053774, DOI: 10.1159/000126946.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCalciumCalcium Channel BlockersCalcium-Transporting ATPasesCell LineEnzyme InhibitorsGonadotropin-Releasing HormoneMembrane PotentialsMiceNeuronsPatch-Clamp TechniquesPotassium ChannelsConceptsGT1-7 cellsGnRH secretory responseGnRH secretionChannel blockersBK channelsSecretory responseGonadotropin-releasing hormone (GnRH) neuronsEffects of charybdotoxinImmortalized GnRH neuronsPerforated-patch recordingsSmall conductance Ca2Patch-clamp recordingsBK channel blockersGamma-aminobutyric acidPatch-clamp techniqueLarge-conductance Ca2Cytoplasmic free Ca2Endoplasmic reticulum Ca2Hormone neuronsGnRH neuronsExcitatory neurotransmitterVoltage-dependent mannerSustained componentFura-2Whole-cell conductance