2009
Innervation of Gonadotropin-Releasing Hormone Neurons by Peptidergic Neurons Conveying Circadian or Energy Balance Information in the Mouse
Ward DR, Dear FM, Ward IA, Anderson SI, Spergel DJ, Smith PA, Ebling FJ. Innervation of Gonadotropin-Releasing Hormone Neurons by Peptidergic Neurons Conveying Circadian or Energy Balance Information in the Mouse. PLOS ONE 2009, 4: e5322. PMID: 19390688, PMCID: PMC2669176, DOI: 10.1371/journal.pone.0005322.Peer-Reviewed Original ResearchConceptsGnRH neuronsVasoactive intestinal peptidePeptidergic neuronsGonadotropin-Releasing Hormone NeuronsGnRH secretory systemVIP-IR fibersGonadotropin-releasing hormoneHypothalamic peptide systemsHormone neuronsBasal forebrainIntestinal peptideHypothalamic neuropeptidesPeptidergic fibersReproductive axisTransgenic miceModulatory inputsNeuronsCircadian timing informationPeptidergic signalsMetabolic statusMiceCircadian informationInnervationSignificant proportionPeptide system
2003
A Confocal Microscopic Study of Gonadotropin-Releasing Hormone (GnRH) Neuron Inputs to Dopaminergic Neurons Containing Estrogen Receptor α in the Arcuate Nucleus of GnRH-Green Fluorescent Protein Transgenic Mice
Mitchell V, Loyens A, Spergel DJ, Flactif M, Poulain P, Tramu G, Beauvillain JC. A Confocal Microscopic Study of Gonadotropin-Releasing Hormone (GnRH) Neuron Inputs to Dopaminergic Neurons Containing Estrogen Receptor α in the Arcuate Nucleus of GnRH-Green Fluorescent Protein Transgenic Mice. Neuroendocrinology 2003, 77: 198-207. PMID: 12673053, DOI: 10.1159/000069511.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsArcuate Nucleus of HypothalamusBrain MappingDopamineEstrogen Receptor alphaFemaleGonadotropin-Releasing HormoneGreen Fluorescent ProteinsHypothalamusLuminescent ProteinsMiceMice, Inbred C57BLMice, TransgenicMicroscopy, ConfocalNerve NetNeural PathwaysNeuronsReceptors, EstrogenTyrosine 3-MonooxygenaseConceptsGnRH-green fluorescent protein transgenic miceTH-ir neuronsTIDA neuronsArcuate nucleusGnRH neuronsDopaminergic neuronsFemale miceTransgenic miceTyrosine hydroxylase-immunoreactive neuronsTH monoclonal antibodyTuberoinfundibular dopaminergic neuronsHydroxylase-immunoreactive neuronsRole of estradiolAdult female miceDouble immunohistochemical stainingEstrogen receptor αGonadotropin-releasing hormone pathwayERalpha activationGnRH fibersImmunoreactive neuronsImmunohistochemical stainingBrain sectionsConfocal microscopic studiesReceptor αEstrus stage