2004
Neurotrophic effects of BDNF on embryonic gonadotropin‐releasing hormone (GnRH) neurons
Cronin AS, Horan TL, Spergel DJ, Brooks AN, Hastings MH, Ebling FJ. Neurotrophic effects of BDNF on embryonic gonadotropin‐releasing hormone (GnRH) neurons. European Journal Of Neuroscience 2004, 20: 338-344. PMID: 15233743, DOI: 10.1111/j.1460-9568.2004.03490.x.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBrainBrain-Derived Neurotrophic FactorCell CountCells, CulturedCyclic AMP Response Element-Binding ProteinDose-Response Relationship, DrugDrug InteractionsEmbryo, MammalianGonadotropin-Releasing HormoneGreen Fluorescent ProteinsImmunoenzyme TechniquesImmunohistochemistryLuminescent ProteinsMiceMice, Inbred C57BLMice, TransgenicMitogen-Activated Protein KinasesNeuritesNeuronsOligodeoxyribonucleotides, AntisensePotassium ChlorideReceptor, trkBConceptsBrain-derived neurotrophic factorGnRH cellsNeurotrophic factorMedian eminenceGonadotropin-releasing hormone (GnRH) neuronsNeurite outgrowthGnRH secretory systemGnRH-immunoreactive cellsGonadotropin-releasing hormoneDose-dependent increaseResponse element-binding proteinPhosphorylation of ERKHormone neuronsBDNF treatmentGnRH neuronsNeurotrophic effectsPreoptic areaNeurons migrateReproductive axisElement-binding proteinOlfactory placodeOlfactory tissuePrimary culturesERK pathwayGnRH
1999
GABA- and Glutamate-Activated Channels in Green Fluorescent Protein-Tagged Gonadotropin-Releasing Hormone Neurons in Transgenic Mice
Spergel D, Krüth U, Hanley D, Sprengel R, Seeburg P. GABA- and Glutamate-Activated Channels in Green Fluorescent Protein-Tagged Gonadotropin-Releasing Hormone Neurons in Transgenic Mice. Journal Of Neuroscience 1999, 19: 2037-2050. PMID: 10066257, PMCID: PMC6782541, DOI: 10.1523/jneurosci.19-06-02037.1999.Peer-Reviewed Original ResearchConceptsGnRH neuronsPreoptic areaNucleated patchesWhole-cell recordingsApplication of GABANMDA receptor channelsGanglion terminaleHormone neuronsOrganum vasculosumSeptal nucleusDiagonal bandLamina terminalisNeuronal somataAxon terminalsOlfactory bulbMedian eminenceTransgenic miceFiring patternsNeuronsNeuronal dendritesReceptor channelsGABAGreen fluorescent proteinL-glutamateAMPA