2004
Neurotrophic effects of BDNF on embryonic gonadotropin‐releasing hormone (GnRH) neurons
Cronin AS, Horan TL, Spergel DJ, Brooks AN, Hastings MH, Ebling FJ. Neurotrophic effects of BDNF on embryonic gonadotropin‐releasing hormone (GnRH) neurons. European Journal Of Neuroscience 2004, 20: 338-344. PMID: 15233743, DOI: 10.1111/j.1460-9568.2004.03490.x.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBrainBrain-Derived Neurotrophic FactorCell CountCells, CulturedCyclic AMP Response Element-Binding ProteinDose-Response Relationship, DrugDrug InteractionsEmbryo, MammalianGonadotropin-Releasing HormoneGreen Fluorescent ProteinsImmunoenzyme TechniquesImmunohistochemistryLuminescent ProteinsMiceMice, Inbred C57BLMice, TransgenicMitogen-Activated Protein KinasesNeuritesNeuronsOligodeoxyribonucleotides, AntisensePotassium ChlorideReceptor, trkBConceptsBrain-derived neurotrophic factorGnRH cellsNeurotrophic factorMedian eminenceGonadotropin-releasing hormone (GnRH) neuronsNeurite outgrowthGnRH secretory systemGnRH-immunoreactive cellsGonadotropin-releasing hormoneDose-dependent increaseResponse element-binding proteinPhosphorylation of ERKHormone neuronsBDNF treatmentGnRH neuronsNeurotrophic effectsPreoptic areaNeurons migrateReproductive axisElement-binding proteinOlfactory placodeOlfactory tissuePrimary culturesERK pathwayGnRH
1994
4 Calcium Signaling and Episodic Secretory Responses of GnRH Neurons
Stojilkovic S, Krsmanovic L, Spergel D, Tomic M, Catt K. 4 Calcium Signaling and Episodic Secretory Responses of GnRH Neurons. International Review Of Neurobiology 1994, 20: 68-84. DOI: 10.1016/b978-0-12-185289-4.50010-3.ChaptersBasal GnRH releaseGnRH releaseGnRH neuronsMammalian gonadotropin-releasing hormoneGnRH pulse generatorPulsatile GnRH releaseGonadotropin-releasing hormoneIntracellular calcium concentrationRelease of neurotransmittersGnRH cellsHypothalamic neuronsPreoptic areaSecretory responseMediobasal hypothalamusHypothalamic tissuePortal vesselsPresynaptic terminalsCalcium concentrationNeuronsCalcium signalingPulsatile natureCellsReleaseSynchronized patternHypothalamus