Vascular tissue engineering: Towards the next generation vascular grafts
Naito Y, Shinoka T, Duncan D, Hibino N, Solomon D, Cleary M, Rathore A, Fein C, Church S, Breuer C. Vascular tissue engineering: Towards the next generation vascular grafts. Advanced Drug Delivery Reviews 2011, 63: 312-323. PMID: 21421015, DOI: 10.1016/j.addr.2011.03.001.Peer-Reviewed Original ResearchConceptsBone marrow-derived mononuclear cellsClinical trialsAutologous bone marrow-derived mononuclear cellsNext-generation vascular graftsMarrow-derived mononuclear cellsVascular graftsExcellent safety profileFirst clinical trialRisk of infectionBiodegradable tubular scaffoldsTissue engineering technologyPrimary graftSafety profileMononuclear cellsCardiovascular diseaseTubular scaffoldsCardiovascular surgeryGraftSynthetic vascular graftsVascular neotissue formationNeotissue formationContinued investigationTEVGsEngineering technologyTrials