Preclinical studies of gossypol in prostate carcinoma.
Naik H, Petrylak D, Yagoda A, Lehr J, Akhtar A, Pienta K. Preclinical studies of gossypol in prostate carcinoma. International Journal Of Oncology 1995, 6: 209-13. PMID: 21556526, DOI: 10.3892/ijo.6.1.209.Peer-Reviewed Original ResearchProstate cancerHuman prostate adenocarcinoma cell line PC-3Hormone-refractory metastatic prostate cancerRefractory metastatic prostate cancerHormone-refractory prostate cancerRefractory prostate cancerMetastatic prostate cancerCell line PC-3MAT-LyLu cellsAnti-spermatogenic effectsPreclinical studiesProstate carcinomaNew agentsCopenhagen ratsDU-145Tumor growthIncurable diseaseMAT-LyLuHigh cytotoxic activityPC-3CancerCytotoxic activityGossypolActive agentsCarcinoma