Strategies to Circumvent Resistance to Apoptosis in Prostate Cancer Cells by Targeted Necrosis
Dinnen R, Petrylak D, Fine R. Strategies to Circumvent Resistance to Apoptosis in Prostate Cancer Cells by Targeted Necrosis. 2009, 327-346. DOI: 10.1007/978-1-4020-9597-9_14.Peer-Reviewed Original ResearchProstate cancer cellsCancer cellsCircumvent resistanceCancer linesHuman prostate cancer cellsProstate cancer cell linesMutant p53Prostate cancer linesNormal cellsCancer cell linesMechanism of cytotoxicityChemotherapy resistanceNecrosisDrug resistanceReactive oxygen speciesHigh levelsSelective killingApoptosisCell linesIntracellular generationNecrotic pathwaysP53Cell deathDeath pathwaysOxygen species