2015
Fatty acid amide supplementation decreases impulsivity in young adult heavy drinkers
van Kooten MJ, Veldhuizen MG, de Araujo IE, O'Malley SS, Small DM. Fatty acid amide supplementation decreases impulsivity in young adult heavy drinkers. Physiology & Behavior 2015, 155: 131-140. PMID: 26656766, PMCID: PMC4718847, DOI: 10.1016/j.physbeh.2015.11.032.Peer-Reviewed Original ResearchConceptsGo/No-Go taskHeavy drinkersStriatal extracellular dopamine levelsVagal afferent signalingExtracellular dopamine levelsHeavy drinking young adultsAlcohol intakeAdult heavy drinkersSupplementation regimenAfferent signalingYoung adult heavy drinkersDopamine levelsSelf-report questionnairesDecrease impulsivityTherapeutic potentialDietary supplementsIntragastric infusionAlcohol useYoung adultsFatty acid amidesPlaceboPreliminary evidenceBehavioral tasksImpulsive respondingImpulsive behavior
2013
Decreased caudate response to milkshake is associated with higher body mass index and greater impulsivity
Babbs RK, Sun X, Felsted J, Chouinard-Decorte F, Veldhuizen MG, Small DM. Decreased caudate response to milkshake is associated with higher body mass index and greater impulsivity. Physiology & Behavior 2013, 121: 103-111. PMID: 23562867, PMCID: PMC3731396, DOI: 10.1016/j.physbeh.2013.03.025.Peer-Reviewed Original ResearchConceptsBody mass indexCaudate responseMass indexCaudate nucleusBrain responsesHigher body mass indexWeight gainHealthy weight subjectsTasteless control solutionEnergy-dense foodsSelf-reported impulsivityWeight subjectsNegative associationVentral putamenDorsal striatumFood rewardDense foodsSignificant associationInverse correlationMilkshakeOverweightGreater impulsivityMeasures of impulsivityGreater responseAssociation