2022
Chronic pain precedes disrupted eating behavior in low-back pain patients
Lin Y, De Araujo I, Stanley G, Small D, Geha P. Chronic pain precedes disrupted eating behavior in low-back pain patients. PLOS ONE 2022, 17: e0263527. PMID: 35143525, PMCID: PMC8830732, DOI: 10.1371/journal.pone.0263527.Peer-Reviewed Original ResearchConceptsLow back pain patientsChronic low back pain patientsFat-rich foodsPain patientsChronic painCLBP patientsSBP patientsNucleus accumbensBack pain patientsChronic pain patientsHealthy control subjectsNucleus accumbens volumePain chronificationFat ingestionHedonic feedingPatient populationAccumbens volumeControl subjectsLimbic brainPainEarly coursePatientsBehavioral alterationsHedonic perceptionNeurological standpoint
2013
Decreased food pleasure and disrupted satiety signals in chronic low back pain
Geha P, deAraujo I, Green B, Small DM. Decreased food pleasure and disrupted satiety signals in chronic low back pain. Pain 2013, 155: 712-722. PMID: 24384160, DOI: 10.1016/j.pain.2013.12.027.Peer-Reviewed Original ResearchConceptsChronic low back painCLBP patientsLow back painHealthy controlsBack painSugary drinksFat calorie intakeHedonic perceptionSatiety signalsCalorie intakePatientsIntake testFood pleasureFunctional brainAd libitumPotential mechanismsPainObesityIntakeStructural alterationsPhysiological mechanismsHedonic ratingsAlterationsDrinksSensory evaluation