2015
Opposing relationships of BMI with BOLD and dopamine D2/3 receptor binding potential in the dorsal striatum
Cosgrove KP, Veldhuizen MG, Sandiego CM, Morris ED, Small DM. Opposing relationships of BMI with BOLD and dopamine D2/3 receptor binding potential in the dorsal striatum. Synapse 2015, 69: 195-202. PMID: 25664726, PMCID: PMC4411955, DOI: 10.1002/syn.21809.Peer-Reviewed Original ResearchConceptsBody mass indexPalatable food consumptionDorsal striatumMass indexBOLD responseReceptor availabilityRelationship of BMIFood consumptionPET studiesMagnetic resonance imaging studyPositron emission tomography studyBlood oxygen level-dependent (BOLD) responseDopamine D2/3 receptorsHigh-fat dietDopamine receptor levelsEmission tomography studiesFMRI studyResonance imaging studyFunctional magnetic resonance imaging studyLevel-dependent responsesReliable inverse relationshipHealthy weightD2/3 receptorsStriatal circuitryFat diet
2005
Gustatory agnosia
Small DM, Bernasconi N, Bernasconi A, Sziklas V, Jones-Gotman M. Gustatory agnosia. Neurology 2005, 64: 311-317. PMID: 15668430, DOI: 10.1212/01.wnl.0000149515.77718.35.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgnosiaAmygdalaAnorexiaAtrophyCerebral CortexElectrodes, ImplantedElectroencephalographyEpilepsy, Temporal LobeFemaleFollow-Up StudiesFood PreferencesHippocampusHumansMagnetic Resonance ImagingMeningoencephalitisNeuropsychological TestsOlfaction DisordersPositron-Emission TomographyPostoperative ComplicationsTasteTaste ThresholdTemporal LobeConceptsMedial temporal lobeTemporal lobeSurgical treatmentLeft medial temporal lobeAnteromedial temporal lobeFunctional neuroimaging studiesBilateral atrophyIntractable epilepsyComplete atrophyPreoperative MRIGustatory functionLeft amygdalaLeft insulaChemosensory evaluationNeuroimaging studiesTaste abilityPatientsAtrophyAmygdalaAversive tasteLobeRecognition thresholdAgnosiaTreatmentTaste quality