2008
Modulation of the spatial attention network by incentives in healthy aging and mild cognitive impairment
Bagurdes LA, Mesulam MM, Gitelman DR, Weintraub S, Small DM. Modulation of the spatial attention network by incentives in healthy aging and mild cognitive impairment. Neuropsychologia 2008, 46: 2943-2948. PMID: 18602410, DOI: 10.1016/j.neuropsychologia.2008.06.005.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAgingAnalysis of VarianceAttentionCase-Control StudiesCerebral CortexCognition DisordersDementiaDiscrimination, PsychologicalHumansLimbic SystemMagnetic Resonance ImagingMatched-Pair AnalysisMiddle AgedMotivationReaction TimeReference ValuesRewardSeverity of Illness IndexSpace PerceptionConceptsSpatial attentionSpatial attention networkAttentional shiftsMild cognitive impairmentAttention networkHealthy agingOrbitofrontal cortexCovert attention taskSelective spatial attentionCognitive impairmentUnderlying neural circuitryAD-related declineAttention taskSelective attentionEmotional contentOFC activationPCC activationSpatial cuesSecondary reinforcerInfluence of incentivesPosterior cingulateNeural circuitryNovel eventsCurrent experimentsBehavioral effects
2001
Changes in Taste Intensity Perception Following Anterior Temporal Lobe Removal in Humans
Small D, Zatorre R, Jones-Gotman M. Changes in Taste Intensity Perception Following Anterior Temporal Lobe Removal in Humans. Chemical Senses 2001, 26: 425-432. PMID: 11369677, DOI: 10.1093/chemse/26.4.425.Peer-Reviewed Original ResearchConceptsAnterior temporal lobeTemporal lobeHealthy control subjectsTemporal lobe removalsRight anterior temporal lobeRight temporal groupPatient groupIntractable epilepsyControl subjectsControl groupMeasures ANOVAMeasures analysisBitter tasteSignificant differencesUnpleasant bitter tasteStimulus concentrationLobeTaste perceptionSubjectsGroupTemporal groupsPatientsIntensity perceptionEpilepsy
1997
Flavor processing
Small D, Jones-Gotman M, Zatorre R, Petrides M, Evans A. Flavor processing. Neuroreport 1997, 8: 3913-3917. PMID: 9462465, DOI: 10.1097/00001756-199712220-00014.Peer-Reviewed Original ResearchMeSH KeywordsAdultCerebrovascular CirculationFemaleHumansMaleReference ValuesSmellTasteTomography, Emission-ComputedConceptsCerebral blood flow changesBlood flow changesSignificant CBF decreasePositron emission tomographySecondary gustatoryCBF decreaseBasal forebrainCBF increaseOlfactory cortexFlavor processingPrimary gustatoryEmission tomographyGustatory stimuliIndependent presentationFlavor conditionFlow changesGustatoryUnpleasant stimuliIdentical stimuliOlfactorySimultaneous presentationPresentationStimuliA Role for the Right Anterior Temporal Lobe in Taste Quality Recognition
Small D, Jones-Gotman M, Zatorre R, Petrides M, Evans A. A Role for the Right Anterior Temporal Lobe in Taste Quality Recognition. Journal Of Neuroscience 1997, 17: 5136-5142. PMID: 9185551, PMCID: PMC6573307, DOI: 10.1523/jneurosci.17-13-05136.1997.Peer-Reviewed Original ResearchConceptsRegional cerebral blood flowAnteromedial temporal lobeGroup of patientsTemporal lobeRight anterior temporal lobectomyOrbitofrontal cortexCaudolateral orbitofrontal cortexAnterior temporal lobectomyCerebral blood flowRight anterior temporal lobePrimary taste cortexTreatment of epilepsyPositron emission tomographyRight cerebral hemisphereAnterior temporal lobeRCBF increasesTemporal lobectomyGustatory functionTaste cortexBlood flowCerebral hemispheresControl groupEmission tomographyPatientsTaste sensation