2015
Fatty acid amide supplementation decreases impulsivity in young adult heavy drinkers
van Kooten MJ, Veldhuizen MG, de Araujo IE, O'Malley SS, Small DM. Fatty acid amide supplementation decreases impulsivity in young adult heavy drinkers. Physiology & Behavior 2015, 155: 131-140. PMID: 26656766, PMCID: PMC4718847, DOI: 10.1016/j.physbeh.2015.11.032.Peer-Reviewed Original ResearchConceptsGo/No-Go taskHeavy drinkersStriatal extracellular dopamine levelsVagal afferent signalingExtracellular dopamine levelsHeavy drinking young adultsAlcohol intakeAdult heavy drinkersSupplementation regimenAfferent signalingYoung adult heavy drinkersDopamine levelsSelf-report questionnairesDecrease impulsivityTherapeutic potentialDietary supplementsIntragastric infusionAlcohol useYoung adultsFatty acid amidesPlaceboPreliminary evidenceBehavioral tasksImpulsive respondingImpulsive behavior
2008
Sleep deprivation alters functioning within the neural network underlying the covert orienting of attention
Mander BA, Reid KJ, Davuluri VK, Small DM, Parrish TB, Mesulam MM, Zee PC, Gitelman DR. Sleep deprivation alters functioning within the neural network underlying the covert orienting of attention. Brain Research 2008, 1217: 148-156. PMID: 18511023, PMCID: PMC2528837, DOI: 10.1016/j.brainres.2008.04.030.Peer-Reviewed Original ResearchConceptsReaction time benefitsFunctional magnetic resonance imagingSpatial attentionPosterior cingulate cortex activationTime benefitsLeft intraparietal sulcusGoal-directed interactionsSleep-deprived individualsSleep deprivation altersInvalid cuesUninformative cuesNeural resourcesValid cuesCovert orientingSelective attentionIrrelevant locationsPCC activationIntraparietal sulcusUpcoming eventsCortex activationBrain activityNormal restPCC activityCuesYoung adults