2018
Supra-Additive Effects of Combining Fat and Carbohydrate on Food Reward
DiFeliceantonio AG, Coppin G, Rigoux L, Thanarajah S, Dagher A, Tittgemeyer M, Small DM. Supra-Additive Effects of Combining Fat and Carbohydrate on Food Reward. Cell Metabolism 2018, 28: 33-44.e3. PMID: 29909968, DOI: 10.1016/j.cmet.2018.05.018.Peer-Reviewed Original Research
2012
Altered hypothalamic response to food in smokers 1 , 2 , 3
Geha PY, Aschenbrenner K, Felsted J, O'Malley SS, Small DM. Altered hypothalamic response to food in smokers 1 , 2 , 3. American Journal Of Clinical Nutrition 2012, 97: 15-22. PMID: 23235196, PMCID: PMC3522134, DOI: 10.3945/ajcn.112.043307.Peer-Reviewed Original ResearchConceptsWeight changeBrain responsesFunctional MRILong-term weight changeAltered brain responsesTasteless control solutionMilk shakeEnergy-dense foodsGroup of ageSmoking statusSmoking cessationSmoking influencesHypothalamic responseNonsmokersSmokersVentral striatumWeight gainBMIHypothalamusGreater responseResponseFoodStudy 1ThalamusGroupFlavor is in the brain
Small DM. Flavor is in the brain. Physiology & Behavior 2012, 107: 540-552. PMID: 22542991, DOI: 10.1016/j.physbeh.2012.04.011.Peer-Reviewed Original Research
2009
The Role of the Parabrachial Nucleus in Taste Processing and Feeding
Scott TR, Small DM. The Role of the Parabrachial Nucleus in Taste Processing and Feeding. Annals Of The New York Academy Of Sciences 2009, 1170: 372-377. PMID: 19686161, DOI: 10.1111/j.1749-6632.2009.03906.x.Peer-Reviewed Original ResearchConceptsParabrachial nucleusVentral forebrainIntegration of tasteSolitary tractForebrain projectionsVisceral sensationOrbitofrontal cortexFeeding behaviorTaste processingHedonic assessmentRodentsCortexForebrainSensory informationActivity parallelPrimatesFood selectionTaste activityNTSEarly recordingsFeedingThalamusReflexSubnucleiHedonic information
2008
Separable Substrates for Anticipatory and Consummatory Food Chemosensation
Small DM, Veldhuizen MG, Felsted J, Mak YE, McGlone F. Separable Substrates for Anticipatory and Consummatory Food Chemosensation. Neuron 2008, 57: 786-797. PMID: 18341997, PMCID: PMC2669434, DOI: 10.1016/j.neuron.2008.01.021.Peer-Reviewed Original Research
2005
Differential Neural Responses Evoked by Orthonasal versus Retronasal Odorant Perception in Humans
Small DM, Gerber JC, Mak YE, Hummel T. Differential Neural Responses Evoked by Orthonasal versus Retronasal Odorant Perception in Humans. Neuron 2005, 47: 593-605. PMID: 16102541, DOI: 10.1016/j.neuron.2005.07.022.Peer-Reviewed Original ResearchConceptsOrbitofrontal cortexCaudolateral orbitofrontal cortexRoute of deliveryInsula/operculumMedial orbitofrontal cortexPerigenual cingulateOral cavityCentral sulcusDifferential neural responsesRetronasal olfactionRetronasal routeBrain responsesNeural responsesNeural recruitmentDifferential activationPreferential activityCortexOdorant perceptionOrthonasalRetronasalDifferential neural recruitmentDeliveryResponseThalamusHippocampus