2016
Effects of the modern food environment on striatal function, cognition and regulation of ingestive behavior
Burke MV, Small DM. Effects of the modern food environment on striatal function, cognition and regulation of ingestive behavior. Current Opinion In Behavioral Sciences 2016, 9: 97-105. PMID: 29619405, PMCID: PMC5879782, DOI: 10.1016/j.cobeha.2016.02.036.Peer-Reviewed Original ResearchFood cue reactivityCue reactivityWeight gain susceptibilityDorsal striatal dopamineEnergy-dense dietInhibitory controlModern food environmentChronic consumptionImpaired inhibitory controlStriatal dopamineStriatal functionStriatal circuitsAnimal studiesBody weightMetabolic diseasesDiet-induced adaptationsPalatable foodDense dietBrain functionIngestive behaviorFood environmentImpair inhibitory controlDietDeleterious influenceNegative outcomes
2014
Working memory and reward association learning impairments in obesity
Coppin G, Nolan-Poupart S, Jones-Gotman M, Small DM. Working memory and reward association learning impairments in obesity. Neuropsychologia 2014, 65: 146-155. PMID: 25447070, PMCID: PMC4259845, DOI: 10.1016/j.neuropsychologia.2014.10.004.Peer-Reviewed Original ResearchConceptsHealthy weight individualsNegative outcomesExplicit learningReward association learningProbabilistic learning taskFunction of groupHealthy weight groupObese individualsReward associationsStimulus-rewardExecutive functionAssociation learningLearning taskExperiment 1Learning impairmentHealthy weightParadoxical preferenceWeight individualsPositive outcomesMemoryWeight groupInfluence of obesitySecond experimentCurrent studyDeficits