Identification of an Amygdala–Thalamic Circuit That Acts as a Central Gain Mechanism in Taste Perceptions
Veldhuizen MG, Farruggia MC, Gao X, Nakamura Y, Green BG, Small DM. Identification of an Amygdala–Thalamic Circuit That Acts as a Central Gain Mechanism in Taste Perceptions. Journal Of Neuroscience 2020, 40: 5051-5062. PMID: 32371606, PMCID: PMC7314406, DOI: 10.1523/jneurosci.2618-19.2020.Peer-Reviewed Original ResearchConceptsTaste intensity perceptionHealthy human participantsFunctional magnetic resonanceVentral posterior medial thalamusPosterior medial thalamusIntensity ratingsMedial dorsalMedial thalamusInhibitory outputInhibitory inputsPeripheral sourcesMagnetic resonanceInhibitory influenceIntensity perceptionCentral circuitsGustatory factorsIndividual variationDynamic causal modeling analysisConnectivity strengthAmygdalaMultiple tastantsGustatory systemMean intensity ratingsTaste intensity ratingsAmygdala response