2020
Identification of an Amygdala–Thalamic Circuit That Acts as a Central Gain Mechanism in Taste Perceptions
Veldhuizen MG, Farruggia MC, Gao X, Nakamura Y, Green BG, Small DM. Identification of an Amygdala–Thalamic Circuit That Acts as a Central Gain Mechanism in Taste Perceptions. Journal Of Neuroscience 2020, 40: 5051-5062. PMID: 32371606, PMCID: PMC7314406, DOI: 10.1523/jneurosci.2618-19.2020.Peer-Reviewed Original ResearchConceptsTaste intensity perceptionHealthy human participantsFunctional magnetic resonanceVentral posterior medial thalamusPosterior medial thalamusIntensity ratingsMedial dorsalMedial thalamusInhibitory outputInhibitory inputsPeripheral sourcesMagnetic resonanceInhibitory influenceIntensity perceptionCentral circuitsGustatory factorsIndividual variationDynamic causal modeling analysisConnectivity strengthAmygdalaMultiple tastantsGustatory systemMean intensity ratingsTaste intensity ratingsAmygdala response
2001
Changes in Taste Intensity Perception Following Anterior Temporal Lobe Removal in Humans
Small D, Zatorre R, Jones-Gotman M. Changes in Taste Intensity Perception Following Anterior Temporal Lobe Removal in Humans. Chemical Senses 2001, 26: 425-432. PMID: 11369677, DOI: 10.1093/chemse/26.4.425.Peer-Reviewed Original ResearchConceptsAnterior temporal lobeTemporal lobeHealthy control subjectsTemporal lobe removalsRight anterior temporal lobeRight temporal groupPatient groupIntractable epilepsyControl subjectsControl groupMeasures ANOVAMeasures analysisBitter tasteSignificant differencesUnpleasant bitter tasteStimulus concentrationLobeTaste perceptionSubjectsGroupTemporal groupsPatientsIntensity perceptionEpilepsy