2016
Reorganization of brain connectivity in obesity
Geha P, Cecchi G, Constable R, Abdallah C, Small DM. Reorganization of brain connectivity in obesity. Human Brain Mapping 2016, 38: 1403-1420. PMID: 27859973, PMCID: PMC6866793, DOI: 10.1002/hbm.23462.Peer-Reviewed Original ResearchConceptsGlobal brain connectivityDorsal attention networkPeripheral metabolic dysfunctionHum Brain MappSuperior parietal lobuleSomatomotor cortexMetabolic dysfunctionVentrolateral prefrontal cortexPremotor areasCaudate nucleusNeurocognitive impairmentObesityAnterior hippocampusVisual cortexBrain regionsParietal lobuleBrain functionPrefrontal cortexBrain connectivityMilkshake consumptionCortexFeeding decisionsBrain organizationInsulaHomeostatic state
2012
The effect of verbal context on olfactory neural responses
Bensafi M, Croy I, Phillips N, Rouby C, Sezille C, Gerber J, Small DM, Hummel T. The effect of verbal context on olfactory neural responses. Human Brain Mapping 2012, 35: 810-818. PMID: 23225581, PMCID: PMC6869804, DOI: 10.1002/hbm.22215.Peer-Reviewed Original ResearchAn fMRI Study of the Interactions Between the Attention and the Gustatory Networks
Veldhuizen MG, Gitelman DR, Small DM. An fMRI Study of the Interactions Between the Attention and the Gustatory Networks. Chemosensory Perception 2012, 5: 117-127. PMID: 25419265, PMCID: PMC4239214, DOI: 10.1007/s12078-012-9122-z.Peer-Reviewed Original ResearchAnterior cingulate cortexFrontal eye fieldCingulate cortexPosterior parietal cortexGustatory cortexEye fieldParietal operculumParietal cortexFrontal operculumAnterior insulaRight anterior insulaPsychophysiological interaction analysisCortexDynamic causal modelingCortex actsIndirect modulationFMRI studyBrain responsesInsulaGoal-directed behaviorIncoming sensory signalsConnectivity analysisSensory signalsCurrent studyAttention task
2010
Evidence for an Integrated Oral Sensory Module in the Human Anterior Ventral Insula
Rudenga K, Green B, Nachtigal D, Small DM. Evidence for an Integrated Oral Sensory Module in the Human Anterior Ventral Insula. Chemical Senses 2010, 35: 693-703. PMID: 20595201, PMCID: PMC2943409, DOI: 10.1093/chemse/bjq068.Peer-Reviewed Original ResearchConceptsAnterior ventral insulaVentral insulaOral stimulationTasteless control solutionFunctional magnetic resonanceVentral pallidumPhysiological significanceHarmful stimuliInsular responsesInsulaOral sensationNutritive stimulusModalitiesDifferential connectivityPresent studyStimulationMagnetic resonanceSensory modalitiesSubjectsHypothalamusStimuliStriatumPallidumThe Insular Taste Cortex Contributes to Odor Quality Coding
Veldhuizen MG, Nachtigal D, Teulings L, Gitelman DR, Small DM. The Insular Taste Cortex Contributes to Odor Quality Coding. Frontiers In Human Neuroscience 2010, 4: 58. PMID: 20700500, PMCID: PMC2917218, DOI: 10.3389/fnhum.2010.00058.Peer-Reviewed Original ResearchCommon central mechanismInsular taste cortexTaste cortexCentral mechanismsFood odorsNon-food odorsOdor quality codingOlfactory cortexInsular cortexOlfactory stimulationCortexCentral pathwaysCortex contributesSweet tasteGustatory systemOlfactory stimuliInsulaStimulationDiscrete mechanismsSensationTaste qualityQuality codingOdor sweetnessPiriformSweetness ratings
2009
Neural correlates of evaluative compared with passive tasting
Bender G, Veldhuizen MG, Meltzer JA, Gitelman DR, Small DM. Neural correlates of evaluative compared with passive tasting. European Journal Of Neuroscience 2009, 30: 327-338. PMID: 19614981, PMCID: PMC2776645, DOI: 10.1111/j.1460-9568.2009.06819.x.Peer-Reviewed Original ResearchConceptsLateral orbitofrontal cortexOrbitofrontal cortexPrimary taste cortexLeft lateral orbitofrontal cortexFunctional magnetic resonanceTasteless solutionMaximal responseTaste cortexFunction of taskCortical representationGustatory informationAnterior insulaVentral regionNeural responsesPreferential connectivityAmygdalaNeural correlatesCortexInsulaNeural encodingSubjectsStimulus presenceMagnetic resonanceResponseEarly relay
2008
Flavor and the Formation of Category-Specific Processing in Olfaction
Small D. Flavor and the Formation of Category-Specific Processing in Olfaction. Chemosensory Perception 2008, 1: 136-146. DOI: 10.1007/s12078-008-9015-3.Peer-Reviewed Original ResearchCategory-specific processingOral referralAnterior cingulate cortexRolandic operculumCingulate cortexPattern of responseOrbitofrontal cortexUnimodal tasteFlavor perceptReferralBimodal cellsCortexNeural processingFlavor objectsSensory modalitiesMultiple sensory modalitiesOlfactionCellsPerception of flavorInsulaNeuronsOperculumNeural bindingResponse
2007
Trying to Detect Taste in a Tasteless Solution: Modulation of Early Gustatory Cortex by Attention to Taste
Veldhuizen MG, Bender G, Constable RT, Small DM. Trying to Detect Taste in a Tasteless Solution: Modulation of Early Gustatory Cortex by Attention to Taste. Chemical Senses 2007, 32: 569-581. PMID: 17495173, DOI: 10.1093/chemse/bjm025.Peer-Reviewed Original Research