Modulation of the spatial attention network by incentives in healthy aging and mild cognitive impairment
Bagurdes LA, Mesulam MM, Gitelman DR, Weintraub S, Small DM. Modulation of the spatial attention network by incentives in healthy aging and mild cognitive impairment. Neuropsychologia 2008, 46: 2943-2948. PMID: 18602410, DOI: 10.1016/j.neuropsychologia.2008.06.005.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAgingAnalysis of VarianceAttentionCase-Control StudiesCerebral CortexCognition DisordersDementiaDiscrimination, PsychologicalHumansLimbic SystemMagnetic Resonance ImagingMatched-Pair AnalysisMiddle AgedMotivationReaction TimeReference ValuesRewardSeverity of Illness IndexSpace PerceptionConceptsSpatial attentionSpatial attention networkAttentional shiftsMild cognitive impairmentAttention networkHealthy agingOrbitofrontal cortexCovert attention taskSelective spatial attentionCognitive impairmentUnderlying neural circuitryAD-related declineAttention taskSelective attentionEmotional contentOFC activationPCC activationSpatial cuesSecondary reinforcerInfluence of incentivesPosterior cingulateNeural circuitryNovel eventsCurrent experimentsBehavioral effectsThe Spatial Attention Network Interacts with Limbic and Monoaminergic Systems to Modulate Motivation-Induced Attention Shifts
Mohanty A, Gitelman DR, Small DM, Mesulam MM. The Spatial Attention Network Interacts with Limbic and Monoaminergic Systems to Modulate Motivation-Induced Attention Shifts. Cerebral Cortex 2008, 18: 2604-2613. PMID: 18308706, PMCID: PMC2567423, DOI: 10.1093/cercor/bhn021.Peer-Reviewed Original ResearchConceptsPosterior parietal cortexSpatial attentionPosterior cingulateAttentional targetsSpatial attention paradigmFood-related cuesStrong functional couplingAttentional biasingAttentional resourcesAttentional shiftsMotivational relevanceAttention paradigmCentral cuesAttention shiftsMotivational salienceMotivational valueMotivational informationMotivational stateMotivational needsIntraparietal sulcusOrbitofrontal cortexParietal cortexFood targetsSelective allocationMultiple domains