2014
Cardiovascular Magnetic Resonance Imaging of Scar Development Following Pulmonary Vein Isolation: A Prospective Study
Hsing J, Peters DC, Knowles BR, Manning WJ, Josephson ME. Cardiovascular Magnetic Resonance Imaging of Scar Development Following Pulmonary Vein Isolation: A Prospective Study. PLOS ONE 2014, 9: e104844. PMID: 25251403, PMCID: PMC4174508, DOI: 10.1371/journal.pone.0104844.Peer-Reviewed Original ResearchMeSH KeywordsAdultAtrial FibrillationCardiovascular SystemCatheter AblationCicatrixContrast MediaEdemaFemaleGadolinium DTPAHumansImage EnhancementLinear ModelsMagnetic Resonance ImagingMaleMiddle AgedProspective StudiesPulmonary VeinsRadiographyReproducibility of ResultsSensitivity and SpecificityTime FactorsConceptsPulmonary vein isolationCardiovascular magnetic resonanceVein isolationAtrial wall thicknessLGE enhancementLGE volumeCardiovascular magnetic resonance imagingVolume of LGEAtrial fibrillation patientsPattern of edemaSubsequent scar formationLate gadolinium enhancement (LGE) imagingMagnetic resonanceAtrial wall thickeningNon-invasive assessmentMagnetic resonance imagingEdema enhancementFibrillation patientsProspective studyPost ablationEarly edemaLGE scarScar formationEdemaResonance imaging
2012
Respiratory bellows‐gated late gadolinium enhancement of the left atrium
Peters DC, Shaw JL, Knowles BR, Moghari MH, Manning WJ. Respiratory bellows‐gated late gadolinium enhancement of the left atrium. Journal Of Magnetic Resonance Imaging 2012, 38: 1210-1214. PMID: 23197465, PMCID: PMC3812253, DOI: 10.1002/jmri.23954.Peer-Reviewed Original ResearchConceptsRight inferior pulmonary veinLate gadolinium enhancementRight superior PVAtrial fibrillationGadolinium enhancementRespiratory compensationScar presenceInferior pulmonary veinNav gatingPresence of scarAtrial imagingSuperior PVBlinded gradingPulmonary veinsLeft atriumTrue scarsPatientsQuadrantScarImproved assessmentFibrillationAtrium
2010
Hypertrophic Cardiomyopathy: Quantification of Late Gadolinium Enhancement with Contrast-enhanced Cardiovascular MR Imaging
Harrigan CJ, Peters DC, Gibson CM, Maron BJ, Manning WJ, Maron MS, Appelbaum E. Hypertrophic Cardiomyopathy: Quantification of Late Gadolinium Enhancement with Contrast-enhanced Cardiovascular MR Imaging. Radiology 2010, 258: 128-33. PMID: 21045187, DOI: 10.1148/radiol.10090526.Peer-Reviewed Original ResearchConceptsLate gadolinium enhancementHypertrophic cardiomyopathyGadolinium enhancementExtent of LGEMean signal intensityCardiovascular magnetic resonance imagingLGE cardiovascular magnetic resonance imagingNormal remote myocardiumVisual assessmentMagnetic resonance imagingInternal Review BoardStudy patientsMean ageBland-Altman analysisLarge cohortRemote myocardiumBody weightMore weeksPatientsSignal intensityResonance imagingGadopentetate dimeglumineMore SDsMR imagingReview board
2009
Left ventricular infarct size, peri‐infarct zone, and papillary scar measurements: A comparison of high‐resolution 3D and conventional 2D late gadolinium enhancement cardiac MR
Peters DC, Appelbaum EA, Nezafat R, Dokhan B, Han Y, Kissinger KV, Goddu B, Manning WJ. Left ventricular infarct size, peri‐infarct zone, and papillary scar measurements: A comparison of high‐resolution 3D and conventional 2D late gadolinium enhancement cardiac MR. Journal Of Magnetic Resonance Imaging 2009, 30: 794-800. PMID: 19787731, PMCID: PMC2981352, DOI: 10.1002/jmri.21897.Peer-Reviewed Original ResearchAssociation of Thrombolysis in Myocardial Infarction Myocardial Perfusion Grade with cardiovascular magnetic resonance measures of infarct architecture after primary percutaneous coronary intervention for ST-segment elevation myocardial infarction
Appelbaum E, Abraham JM, Pride YB, Harrigan CJ, Peters DC, Biller LH, Manning WJ, Gibson CM. Association of Thrombolysis in Myocardial Infarction Myocardial Perfusion Grade with cardiovascular magnetic resonance measures of infarct architecture after primary percutaneous coronary intervention for ST-segment elevation myocardial infarction. American Heart Journal 2009, 158: 84-91. PMID: 19540396, DOI: 10.1016/j.ahj.2009.04.012.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAngioplasty, Balloon, CoronaryCardiac VolumeContrast MediaCoronary AngiographyCoronary CirculationElectrocardiographyEndocardiumFemaleGadolinium DTPAHeart VentriclesHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMiddle AgedMyocardial InfarctionMyocardial Reperfusion InjuryMyocardiumPericardiumPrognosisSignal Processing, Computer-AssistedThrombolytic TherapyTreatment OutcomeConceptsST-segment elevation myocardial infarctionPrimary percutaneous coronary interventionMyocardial perfusion gradeInfarct border zoneMyocardial Infarction (TIMI) myocardial perfusion gradeElevation myocardial infarctionPercutaneous coronary interventionInfarct sizePerfusion gradeMyocardial perfusionInfarct surface areaCoronary interventionMyocardial infarctionInfarct architectureCardiovascular magnetic resonance measuresNormal epicardial flowDays of presentationMagnetic resonance measuresCardiovascular magnetic resonanceImpaired thrombolysisEpicardial flowThrombolysisPatientsPerfusionTMPGRecurrence of Atrial Fibrillation Correlates With the Extent of Post-Procedural Late Gadolinium Enhancement A Pilot Study
Peters DC, Wylie JV, Hauser TH, Nezafat R, Han Y, Woo JJ, Taclas J, Kissinger KV, Goddu B, Josephson ME, Manning WJ. Recurrence of Atrial Fibrillation Correlates With the Extent of Post-Procedural Late Gadolinium Enhancement A Pilot Study. JACC Cardiovascular Imaging 2009, 2: 308-316. PMID: 19356576, PMCID: PMC2703450, DOI: 10.1016/j.jcmg.2008.10.016.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAtrial FibrillationCatheter AblationCicatrixContrast MediaFemaleGadolinium DTPAHeart AtriaHumansImage Interpretation, Computer-AssistedImaging, Three-DimensionalKaplan-Meier EstimateMagnetic Resonance ImagingMaleMiddle AgedPilot ProjectsPredictive Value of TestsProportional Hazards ModelsPulmonary VeinsRecurrenceRisk AssessmentTime FactorsTreatment FailureConceptsRight inferior pulmonary veinCardiac magnetic resonanceLGE cardiac magnetic resonanceRF ablation proceduresPulmonary veinsAF recurrenceAblation proceduresPV isolationLate gadolinium enhancement (LGE) CMRAtrial fibrillation correlatesBidirectional conduction blockAtrial fibrillation patientsInferior pulmonary veinExtent of scarringRadiofrequency ablation lesionsExtent of scarA Pilot StudyFirst yearRecurrent AFThirteen patientsFibrillation patientsParoxysmal AFPV ostiaProcedural successAtrial scarring
2008
Cardiovascular Magnetic Resonance Characterization of Mitral Valve Prolapse
Han Y, Peters DC, Salton CJ, Bzymek D, Nezafat R, Goddu B, Kissinger KV, Zimetbaum PJ, Manning WJ, Yeon SB. Cardiovascular Magnetic Resonance Characterization of Mitral Valve Prolapse. JACC Cardiovascular Imaging 2008, 1: 294-303. PMID: 19356441, DOI: 10.1016/j.jcmg.2008.01.013.Peer-Reviewed Original ResearchMeSH KeywordsArrhythmias, CardiacCase-Control StudiesContrast MediaEchocardiography, DopplerFibrosisGadolinium DTPAHumansImaging, Three-DimensionalMagnetic Resonance Imaging, CineMitral ValveMitral Valve ProlapsePapillary MusclesPredictive Value of TestsProspective StudiesSensitivity and SpecificityConceptsMitral valve prolapseComplex ventricular arrhythmiasMVP patientsMitral annular diameterValve prolapseControl subjectsPapillary musclesTransthoracic echocardiographyVentricular arrhythmiasAnnular diameterDiagnostic criteriaCardiovascular magnetic resonance characterizationCommon valvular heart diseaseLeft ventricular outflow tractCMR diagnostic criteriaSubgroup of patientsValvular heart diseaseVentricular outflow tractGold standardLate gadolinium enhancementCardiovascular magnetic resonanceMitral valve morphologyValuable imaging toolClinical gold standardControl patients
2005
Pulmonary vein imaging: comparison of 3D magnetic resonance angiography with 2D cine MRI for characterizing anatomy and size.
Syed MA, Peters DC, Rashid H, Arai AE. Pulmonary vein imaging: comparison of 3D magnetic resonance angiography with 2D cine MRI for characterizing anatomy and size. Journal Of Cardiovascular Magnetic Resonance 2005, 7: 355-60. PMID: 15881514, DOI: 10.1081/jcmr-200053458.Peer-Reviewed Original ResearchConceptsPulmonary vein ostial diametersMagnetic resonance angiographyPulmonary veinsCine CMROstial diameterNormal volunteersResonance angiographyAtrial fibrillation ablation proceduresAtrial fibrillation patientsPulmonary vein diameterCardiac magnetic resonanceCine cardiac magnetic resonanceThree-dimensional magnetic resonance angiographyContrast-enhanced 3D MRAFibrillation patientsAtrial fibrillationVein diameterAblation proceduresAnatomical depictionPatientsT scannerAngiographyCine MRICMRVein
2003
Magnetic Resonance Fluoroscopy Allows Targeted Delivery of Mesenchymal Stem Cells to Infarct Borders in Swine
Dick AJ, Guttman MA, Raman VK, Peters DC, Pessanha BS, Hill JM, Smith S, Scott G, McVeigh ER, Lederman RJ. Magnetic Resonance Fluoroscopy Allows Targeted Delivery of Mesenchymal Stem Cells to Infarct Borders in Swine. Circulation 2003, 108: 2899-2904. PMID: 14656911, PMCID: PMC1325104, DOI: 10.1161/01.cir.0000095790.28368.f9.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCardiac CatheterizationComputer SystemsContrast MediaFeasibility StudiesFerrosoferric OxideGadolinium DTPAImaging, Three-DimensionalIronMagnetic Resonance ImagingMesenchymal Stem Cell TransplantationMicroscopy, FluorescenceMicrospheresMyocardial InfarctionOxidesPhantoms, ImagingSafetySwine, MiniatureTransplantation, Homologous
2002
Catheter-Based Endomyocardial Injection With Real-Time Magnetic Resonance Imaging
Lederman RJ, Guttman MA, Peters DC, Thompson RB, Sorger JM, Dick AJ, Raman VK, McVeigh ER. Catheter-Based Endomyocardial Injection With Real-Time Magnetic Resonance Imaging. Circulation 2002, 105: 1282-1284. PMID: 11901036, PMCID: PMC1317571, DOI: 10.1161/circ.105.11.1282.Peer-Reviewed Original ResearchConceptsReal-time MRIMRI-compatible needleFirst generation prototypeRtMRI guidanceEndomyocardial injectionNeedle injectorReconstruction engineLeft ventricular cavityMagnetic resonance imagingTime magnetic resonance imagingMyocardial segmentsT MRI scannerVentricular cavityGadolinium-DTPAResonance imagingDrug deliveryLV wallCatheter navigationMultiple injectionsInjectionInjectorEngineMRI scannerCoilImaging softwareMultislice first‐pass cardiac perfusion MRI: Validation in a model of myocardial infarction†
Epstein FH, London JF, Peters DC, Goncalves LM, Agyeman K, Taylor J, Balaban RS, Arai AE. Multislice first‐pass cardiac perfusion MRI: Validation in a model of myocardial infarction†. Magnetic Resonance In Medicine 2002, 47: 482-491. PMID: 11870835, DOI: 10.1002/mrm.10085.Peer-Reviewed Original Research