IL-7 plays a critical role for the homeostasis of allergen-specific memory CD4 T cells in the lung and airways
Yeon SM, Halim L, Chandele A, Perry CJ, Kim SH, Kim SU, Byun Y, Yuk SH, Kaech SM, Jung YW. IL-7 plays a critical role for the homeostasis of allergen-specific memory CD4 T cells in the lung and airways. Scientific Reports 2017, 7: 11155. PMID: 28894184, PMCID: PMC5593957, DOI: 10.1038/s41598-017-11492-7.Peer-Reviewed Original ResearchConceptsMediastinal lymph nodesCD4 T cellsMemory T cellsT cellsAllergen-specific memory T cellsMemory CD4 T cellsMemory Th2 cellsIL-7 signalingAirway inflammationAllergen exposureAntigen exposureLymph nodesAllergic diseasesHomeostatic proliferationAllergic patientsRecall responsesTh2 cellsIL-7Murine modelAirwayViral infectionLungDependent fashionHomeostatic turnoverCells