CCR7 expression alters memory CD8 T-cell homeostasis by regulating occupancy in IL-7– and IL-15–dependent niches
Jung YW, Kim HG, Perry CJ, Kaech SM. CCR7 expression alters memory CD8 T-cell homeostasis by regulating occupancy in IL-7– and IL-15–dependent niches. Proceedings Of The National Academy Of Sciences Of The United States Of America 2016, 113: 8278-8283. PMID: 27385825, PMCID: PMC4961181, DOI: 10.1073/pnas.1602899113.Peer-Reviewed Original ResearchConceptsC receptor 7Memory T cellsMemory CD8 T-cell homeostasisMemory CD8 T cellsCD8 T cell homeostasisCD8 T cellsT cellsT cell homeostasisIL-15IL-7Different memory T-cell subsetsMemory CD8 T cell poolCD8 T cell poolLymphocytic choriomeningitis virus infectionMemory T cell subsetsHomeostasis of effectorAcute viral infectionT cell poolT cell subsetsT cell zonesDendritic cellsLymph nodesPredominant cytokineReceptor 7Chemokine receptors