2006
Utilization of Endoplasmic Reticulum Membranes to Establish a Vacuole that Supports Replication of Legionella pneumophila
Stein M, Roy C. Utilization of Endoplasmic Reticulum Membranes to Establish a Vacuole that Supports Replication of Legionella pneumophila. 2006, 199-210. DOI: 10.1002/352760880x.ch11.Peer-Reviewed Original ResearchAutophagy machineryAutophagy mutantsHost autophagy machineryAutophagosome maturationMorphological differencesOther BacteriaLegionella replicationAutophagy formationEndoplasmic reticulum membraneReticulum membraneMutantsAutophagosomesMachineryAutophagyBiogenesisLegionella pneumophilaVacuolesBacteriaReplicationLCVMaturationLegionellaInduction
1999
Pore‐forming activity is not sufficient for Legionella pneumophila phagosome trafficking and intracellular growth
Zuckman D, Hung J, Roy C. Pore‐forming activity is not sufficient for Legionella pneumophila phagosome trafficking and intracellular growth. Molecular Microbiology 1999, 32: 990-1001. PMID: 10361301, DOI: 10.1046/j.1365-2958.1999.01410.x.Peer-Reviewed Original ResearchConceptsPhagosome traffickingPhagosome-lysosome fusionIntracellular growthLysosome fusionEukaryotic cellular processesInsertion of poresPore-forming activityL. pneumophila mutantsHost cell cytoplasmCellular processesMammalian cellsReplicative nicheSimilar cytolytic activityGene productsPhagosome membraneIntracellular bacteriaTraffickingCell cytoplasmEffector moleculesBacterial pathogensLegionella pneumophilaMacrophage membraneVirulent bacteriaBacteriaFusion inhibition