Optimising predictive models to prioritise viral discovery in zoonotic reservoirs
Becker D, Albery G, Sjodin A, Poisot T, Bergner L, Chen B, Cohen L, Dallas T, Eskew E, Fagre A, Farrell M, Guth S, Han B, Simmons N, Stock M, Teeling E, Carlson C. Optimising predictive models to prioritise viral discovery in zoonotic reservoirs. The Lancet Microbe 2022, 3: e625-e637. PMID: 35036970, PMCID: PMC8747432, DOI: 10.1016/s2666-5247(21)00245-7.Peer-Reviewed Original ResearchConceptsSystematic model validationTrait-based modelsHost-virus associationsBat hostsHost ecologyWildlife samplesBat speciesNovel hostsSampling recommendationsBridge hostsWildlifeWildlife reservoirsTarget prioritisationBatsStatistical modelMachine learning modelsModel performanceViral discoveryProcess of predictionAnalytical pipelinePrediction modelBetacoronavirusLearning modelsEcologyEnsemble model